Literature DB >> 6651832

Rat atrial natriuretic factor. Purification and vasorelaxant activity.

R T Grammer, H Fukumi, T Inagami, K S Misono.   

Abstract

The atrial natriuretic activity of rat heart has been found to exist in multiple forms. One of these factors has been purified to apparent homogeneity by a combination of gel filtration and high pressure liquid chromatography in two different systems and its amino acid composition determined. The purified active peptide is shown to have a molecular weight of approximately 3800. In addition, the vasorelaxant activity of rat atrium has been purified and found to co-chromatograph with the natriuretic activity in all chromatographic systems employed. Thus, the vasorelaxant activity resides in the natriuretic factor. The existence of this new multifunctional peptide implies a higher level of complexity for cardiovascular control of blood volume and pressure.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6651832     DOI： 10.1016/0006-291x(83)90581-8

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  18 in total

Review 1.  Natriuretic peptide receptor: structure and signaling.

Authors:  Kunio S Misono
Journal:  Mol Cell Biochem       Date:  2002-01       Impact factor: 3.396

2.  Kinetic analysis of internalization, recycling and redistribution of atrial natriuretic factor-receptor complex in cultured vascular smooth-muscle cells. Ligand-dependent receptor down-regulation.

Authors:  K N Pandey
Journal:  Biochem J       Date:  1992-11-15       Impact factor: 3.857

Review 3.  Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase.

Authors:  Kunio S Misono; John S Philo; Tsutomu Arakawa; Craig M Ogata; Yue Qiu; Haruo Ogawa; Howard S Young
Journal:  FEBS J       Date:  2011-04-07       Impact factor: 5.542

4.  Visualisation of specific binding sites for atrial natriuretic peptide on non-neuronal cells of cultured rat sympathetic ganglia.

Authors:  S James; C J Hassall; J M Polak; G Burnstock
Journal:  Cell Tissue Res       Date:  1990-01       Impact factor: 5.249

Review 5.  The biochemistry and molecular biology of atrial natriuretic factor.

Authors:  T G Flynn; P L Davies
Journal:  Biochem J       Date:  1985-12-01       Impact factor: 3.857

Review 6.  The atrial natriuretic factor.

Authors:  J Genest
Journal:  Br Heart J       Date:  1986-10

Review 7.  Congestive cardiac failure: central role of the arterial blood pressure.

Authors:  P Harris
Journal:  Br Heart J       Date:  1987-09

8.  Characterization and distribution of receptors for the atrial natriuretic peptides in mammalian brain.

Authors:  R Quirion; M Dalpé; T V Dam
Journal:  Proc Natl Acad Sci U S A       Date:  1986-01       Impact factor: 11.205

Review 9.  The renal paracrine peptide system--possible urologic implications of urodilatin.

Authors:  M Meyer; C G Stief; A J Becker; M C Truss; A Taher; U Jonas; W G Forssmann
Journal:  World J Urol       Date:  1996       Impact factor: 4.226

10.  Reversibly bound chloride in the atrial natriuretic peptide receptor hormone-binding domain: possible allosteric regulation and a conserved structural motif for the chloride-binding site.

Authors:  Haruo Ogawa; Yue Qiu; John S Philo; Tsutomu Arakawa; Craig M Ogata; Kunio S Misono
Journal:  Protein Sci       Date:  2010-03       Impact factor: 6.725
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.