Literature DB >> 6651769

The presence of polysaccharide in normal human gastric mucus.

J R Clamp, B Cooper, J M Creeth, D Ene, J Barrett, M Gough.   

Abstract

Polysaccharide material was found in the proteolysis glycopolypeptide fraction from normal human gastric mucus. The polysaccharide was identified by carbohydrate and amino acid analyses, by elemental analysis and from its behaviour on density-gradient ultracentrifugation. The polysaccharide is polydisperse with a weight-average molecular mass of 300 000 Da. Over 85% of the polysaccharide consists of galactose, and this represents 26% of all the galactose present in the fractions after beta-elimination with reduction of the glycopolypeptide material.

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Year:  1983        PMID： 6651769      PMCID： PMC1152412          DOI： 10.1042/bj2150421

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  7 in total

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Authors:  L Reid; J R Clamp
Journal:  Br Med Bull       Date:  1978-01       Impact factor: 4.291

Review 2.  Mucus of the mammalian genital tract.

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Journal:  Br Med Bull       Date:  1978-01       Impact factor: 4.291

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Journal:  J Biol Chem       Date:  1968-02-10       Impact factor: 5.157

4.  The macromolecular properties of blood-group-specific glycoproteins. Characterization of a series of fractions obtained by solvent fractionation.

Authors:  K R Bhaskar; A S Donald; W T Morgan; J C Creeth
Journal:  Biochem J       Date:  1974-10       Impact factor: 3.857

5.  Study of the carbohydrate content of mucus glycoproteins from normal and diseased colons.

Authors:  J R Clamp; G Fraser; A E Read
Journal:  Clin Sci (Lond)       Date:  1981-08       Impact factor: 6.124

6.  A gas-liquid chromatographic approach to the analysis of carbohydrates.

Authors:  J R Clamp
Journal:  Biochem Soc Trans       Date:  1977       Impact factor: 5.407

7.  Gastric mucus: isolation and polymeric structure of the undegraded glycoprotein: its breakdown by pepsin.

Authors:  J Pearson; A Allen; C Venables
Journal:  Gastroenterology       Date:  1980-04       Impact factor: 22.682
  7 in total
  5 in total

1.  A study of macromolecular diffusion through native porcine mucus.

Authors:  M A Desai; M Mutlu; P Vadgama
Journal:  Experientia       Date:  1992-01-15

2.  Characterization of the major and minor mucus glycoproteins from bovine submandibular gland.

Authors:  A P Corfield; C D Corfield; R W Veh; S A Wagner; J R Clamp; R Schauer
Journal:  Glycoconj J       Date:  1991-08       Impact factor: 2.916

3.  The roles of enteric bacterial sialidase, sialate O-acetyl esterase and glycosulfatase in the degradation of human colonic mucin.

Authors:  A P Corfield; S A Wagner; L J O'Donnell; P Durdey; R A Mountford; J R Clamp
Journal:  Glycoconj J       Date:  1993-02       Impact factor: 2.916

4.  Effect of N-methyl-N'-nitro-N-nitrosoguanidine on carbohydrate profiles of non-metaplastic rat gastric mucosa.

Authors:  H P Sinn; A de Oliveira Neto; T Lehnert; E E Deschner
Journal:  J Cancer Res Clin Oncol       Date:  1993       Impact factor: 4.553

5.  Metagenomes of rectal swabs in larger, advanced stage cervical cancers have enhanced mucus degrading functionalities and distinct taxonomic structure.

Authors:  Tatiana V Karpinets; Xiaogang Wu; Travis Solley; Molly B El Alam; Travis T Sims; Kyoko Yoshida-Court; Erica Lynn; Mustapha Ahmed-Kaddar; Greyson Biegert; Jingyan Yue; Xingzhi Song; Huandong Sun; Joseph F Petrosino; Melissa P Mezzari; Pablo Okhuysen; Patricia J Eifel; Anuja Jhingran; Lilie L Lin; Kathleen M Schmeler; Lois Ramondetta; Nadim Ajami; Robert R Jenq; Andrew Futreal; Jianhua Zhang; Ann H Klopp; Lauren E Colbert
Journal:  BMC Cancer       Date:  2022-09-01       Impact factor: 4.638
  5 in total

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