| Literature DB >> 6651739 |
Abstract
The chronotropic response (delta rate) to histamine of atria from estradiol 17-beta (E2; 0.1 mg/kg)-treated (14 days) rabbit was significantly greater compared to those from control rabbits. However, the maximum response of atria from rabbits treated with a higher dose of E2 (1.0 mg/kg) was not significantly different from control. Cimetidine (2.8 X 10(-7) M) inhibited the theoretical maximum income in rate to histamine in all 3 groups, control 25%, E2 (0.1 mg) 42% and E2 (1.0 mg) 35%.Entities:
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Year: 1983 PMID： 6651739 DOI： 10.1007/BF01906461
Source DB: PubMed Journal: Basic Res Cardiol ISSN： 0300-8428 Impact factor: 17.165