Literature DB >> 6648970

A new mass screening method for determining UDP-galactose in blood.

Y Fujimura, M Kawamura, H Naruse.   

Abstract

We devised a new microfluorometric mass screening method for determining UDP-galactose by using only one blood disc of 3 mm in diameter. This method contains two coupling enzymes of UDP-galactose-4-epimerase and UDP-glucose dehydrogenase, and conversion of NAD to NADH. The assay ranges are 0 to 1 mM or 0 to 0.2 mM UDP-galactose in blood. UDP-galactose contents were determined in galactosemia of epimerase-, transferase- and kinase-deficiencies, and several cases with high or low Paigen's values.

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Year:  1983        PMID: 6648970     DOI: 10.1620/tjem.141.263

Source DB:  PubMed          Journal:  Tohoku J Exp Med        ISSN: 0040-8727            Impact factor:   1.848


  2 in total

1.  Deficit of uridine diphosphate galactose in galactosaemia.

Authors:  W G Ng; Y K Xu; F R Kaufman; G N Donnell
Journal:  J Inherit Metab Dis       Date:  1989       Impact factor: 4.982

2.  Uridine nucleotide sugars in erythrocytes of patients with galactokinase deficiency.

Authors:  Y K Xu; W G Ng; F R Kaufman; G N Donnell
Journal:  J Inherit Metab Dis       Date:  1989       Impact factor: 4.982

  2 in total

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