Literature DB >> 6648949

Endemic HBV infection, tissue autoantibodies and HLA. Analysis of a Sardinian population.

A Carbonara, W Mayr, M Rizzetto, L Contu, E S Curtoni, M DeMarchi, P Farci, C Lavarini, E Olivetti.   

Abstract

Serum samples of 405 HLA-typed individuals from four Sardinian villages were analyzed for HB virus markers and for tissue autoantibodies. Of the 59% individuals who had been exposed to HBV, 10% were healthy carriers; they showed a weak association with the HLA-B40 specificity compared with the immune or non-exposed groups, and a negative association of DR4, limited to females. Tissue autoantibodies were significantly associated with DR1 and more weakly with B14, probably through linkage disequilibrium.

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Year:  1983        PMID: 6648949     DOI: 10.1111/j.1399-0039.1983.tb01205.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN: 0001-2815


  2 in total

1.  Defects in antigen presentation of mutant influenza haemagglutinins are reversed by mutations in the MHC class II molecule.

Authors:  A P Warren; I Paschedag; C Benoist; J Peccoud; D Mathis; D B Thomas
Journal:  EMBO J       Date:  1990-12       Impact factor: 11.598

Review 2.  Quantitative genetics in the study of virus-induced disease.

Authors:  Martin T Ferris; Mark T Heise
Journal:  Adv Virus Res       Date:  2014       Impact factor: 9.937

  2 in total

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