| Literature DB >> 6648509 |
P Tachon, A Laschi, J P Briffaux, G Brain, P Chambon.
Abstract
Twenty-two female monkeys (Macaca irus) were given lead acetate by an intramuscular route during pregnancy and/or lactation. A high dose of lead (5 mg Pb2+/kg/day) can induce abortions and death in pregnant monkeys. At a lower dose (1 mg Pb2+/kg/day), the foetus can be exposed to lead via placenta and/or maternal milk. Studies using optical microscopy showed the typical renal lesions in mothers treated during pregnancy (five months) and an erythrodiapedesis in cerebral matter of the new-born at birth.Entities:
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Year: 1983 PMID： 6648509 DOI： 10.1016/0048-9697(83)90014-1
Source DB: PubMed Journal: Sci Total Environ ISSN： 0048-9697 Impact factor: 7.963