Literature DB >> 6648019

First experimental and clinical results of isolated liver perfusion with cytotoxics in metastases from colorectal primary.

K Aigner, H Walther, J Tonn, A Wenzl, R Hechtel, G Merker, K Schwemmle.   

Abstract

In two patients suffering from numerous liver metastases in both lobes from colorectal primary isolated liverperfusion with 5-fluorouracil was performed. By means of a special cannulation system the hepatic artery and the portal vein were arterialized. The patients recovered rapidly after the operation. Sonographic measurements, CAT scans, pulse cytophotometry, and second-look operations with histological examinations of metastatic tissue verified extensive tumor regression. No complications occurred within 6 months after the perfusion treatment.

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Year:  1983        PMID： 6648019     DOI： 10.1007/978-3-642-82025-0_18

Source DB:  PubMed          Journal:  Recent Results Cancer Res        ISSN： 0080-0015


  9 in total

Review 1.  Isolated hepatic perfusion for patients with liver metastases.

Authors:  Srinevas K Reddy; Susan B Kesmodel; H Richard Alexander
Journal:  Ther Adv Med Oncol       Date:  2014-07       Impact factor: 8.168

2.  Feasible model for locoregional and systemic longterm administration of drugs and concomitant blood sampling in Sprague-Dawley rats.

Authors:  J L Aguiar; R Bartkowski; M R Berger; E Petru; P Schlag; D Schmähl
Journal:  J Cancer Res Clin Oncol       Date:  1987       Impact factor: 4.553

3.  Regression of established macroscopic liver metastases after in situ transduction of a suicide gene.

Authors:  M Caruso; Y Panis; S Gagandeep; D Houssin; J L Salzmann; D Klatzmann
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-01       Impact factor: 11.205

4.  Regional chemotherapy for melanoma. A 35-year experience.

Authors:  E T Krementz; R D Carter; C M Sutherland; J H Muchmore; R F Ryan; O Creech
Journal:  Ann Surg       Date:  1994-10       Impact factor: 12.969

5.  Experiments on the efficacy and toxicity of locoregional chemotherapy of liver tumors with 5-fluoro-2'-deoxyuridine (FUDR) and 5-fluorouracil (5-FU) in an animal model.

Authors:  R Bartkowski; M R Berger; J L Aguiar; T H Henne; J Dörsam; G H Geelhaar; P Schlag; C Herfarth
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

6.  Leukocyte activation by isolated hyperthermic liver and limb perfusion due to malignancy.

Authors:  J P Arnestad; A Bengtsson; J P Bengtson; L Hafström; H Redl; G Schlag
Journal:  World J Surg       Date:  1995 Nov-Dec       Impact factor: 3.352

7.  The vascularization of liver metastases. Histological investigation of gelatine-injected liver specimens with special regard to the vascularization of micrometastases.

Authors:  G Haugeberg; T Strohmeyer; W Lierse; W Böcker
Journal:  J Cancer Res Clin Oncol       Date:  1988       Impact factor: 4.553

Review 8.  Percutaneous Isolated Hepatic Perfusion for the Treatment of Unresectable Liver Malignancies.

Authors:  Mark C Burgmans; Eleonora M de Leede; Christian H Martini; Ellen Kapiteijn; Alexander L Vahrmeijer; Arian R van Erkel
Journal:  Cardiovasc Intervent Radiol       Date:  2015-12-30       Impact factor: 2.740

9.  Prospective evaluation of percutaneous hepatic perfusion with melphalan as a treatment for unresectable liver metastases from colorectal cancer.

Authors:  T Susanna Meijer; Jan H N Dieters; Eleonora M de Leede; Lioe-Fee de Geus-Oei; Jaap Vuijk; Christian H Martini; Arian R van Erkel; Jacob Lutjeboer; Rutger W van der Meer; Fred G J Tijl; Ellen Kapiteijn; Alexander L Vahrmeijer; Mark C Burgmans
Journal:  PLoS One       Date:  2022-01-13       Impact factor: 3.240
  9 in total

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