Literature DB >> 6644705

Acetylator phenotype and the effect of dapsone in rheumatoid arthritis.

P R Crook, C Hortas, E J Roberts, D R Swinson, J C Mucklow, M F Shadforth.   

Abstract

Acetylator phenotype was determined in 54 patients with rheumatoid arthritis (RA) taking dapsone in the course of 2 comparative clinical studies. No significant differences were demonstrated in the assessments, either of efficacy or adverse effects. There appears to be no clinical advantage in assessing acetylator phenotype in patients with RA being treated with dapsone.

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Year:  1983        PMID: 6644705

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  2 in total

1.  Effect of acetylator phenotype on efficacy and toxicity of sulphasalazine in rheumatoid arthritis.

Authors:  T Pullar; J A Hunter; H A Capell
Journal:  Ann Rheum Dis       Date:  1985-12       Impact factor: 19.103

2.  Acetylator polymorphism in rheumatoid arthritis.

Authors:  J M Ladero; M P Andres; A Bañares; B Fernández; C Hernández; J Benítez
Journal:  Eur J Clin Pharmacol       Date:  1993       Impact factor: 2.953

  2 in total

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