Synthesis of 73As-radiolabelled arsenobetaine and arsenocholine for metabolic studies and their fate and distribution in laboratory animals.

73As-labelled arsenobetaine and arsenocholine have been synthesized in mg scales in this laboratory. Specific radioactivities in the range of 100 muCi (3.7 MBq) 73As/mg As have been employed. Further purification of the synthesized compounds has been performed by ion exchange chromatography.