Literature DB >> 6642134

Vincristine-resistant P388 leukemia cells contain a large amount of calcium.

T Tsuruo, H Iida, S Tsukagoshi, Y Sakurai.   

Abstract

P388 leukemia cells resistant to vincristine contained more calcium in the cells than the parent sensitive line, especially in the form of EGTA-removable (surface-bound) calcium. Although the relationship, if any, between the high cellular calcium of resistant cells and drug-resistant phenotype is not clear, the possible implications of this result for the elucidation of the mechanisms of drug resistance are interesting.

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Year:  1983        PMID: 6642134

Source DB:  PubMed          Journal:  Gan        ISSN: 0016-450X


  2 in total

1.  Ultrastructural evaluation of murine bladder epithelium exposed to verapamil.

Authors:  M T Tseng; W Simpson; J I Harty
Journal:  Urol Res       Date:  1985

2.  3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From Calcium-Channel Modulators Properties to Multidrug-Resistance Reverting Activity.

Authors:  Matteo Micucci; Maurizio Viale; Alberto Chiarini; Domenico Spinelli; Maria Frosini; Cinzia Tavani; Massimo Maccagno; Lara Bianchi; Rosaria Gangemi; Roberta Budriesi
Journal:  Molecules       Date:  2020-02-27       Impact factor: 4.411

  2 in total

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