Literature DB >> 6641903

Gossypol. Synthesis and in vitro spermicidal activity of isomeric hemigossypol derivatives.

A Manmade, P Herlihy, J Quick, R P Duffley, M Burgos, A P Hoffer.   

Abstract

Three isomeric hemigossypol derivatives (3,4,5) have been synthesized. Two of these derivatives (3,4) and one synthetic intermediate (7) have been shown to have activity comparable to gossypol (1) in a sperm motility assay.

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Year:  1983        PMID: 6641903     DOI: 10.1007/BF01990368

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  2 in total

1.  In vitjro spermicidal activity of gossypol.

Authors:  D P Waller; L J Zaneveld; H H Fong
Journal:  Contraception       Date:  1980-08       Impact factor: 3.375

2.  Effects of gossypol on the seminiferous epithelium in the rat: a light and electron microscope study.

Authors:  A P Hoffer
Journal:  Biol Reprod       Date:  1983-05       Impact factor: 4.285

  2 in total
  1 in total

1.  Synthesis of Hemigossypol and its Derivatives.

Authors:  Jun Wei; David L Vander Jagt; Robert E Royer; Lorraine M Deck
Journal:  Tetrahedron Lett       Date:  2010-08-30       Impact factor: 2.415

  1 in total

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