Literature DB >> 6640457

Prolonged delirium without anticholinergic signs following amitriptyline overdose.

I H Gomolin, C A Melmed.   

Abstract

In a case of acute intoxication with a tricyclic antidepressant (amitriptyline) delirium was prolonged without there being prominent peripheral anticholinergic or electrocardiographic signs. Administration of physostigmine, repeated when necessary, reversed the delirium.

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Year:  1983        PMID： 6640457      PMCID： PMC1875538     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN： 0008-4409            Impact factor:   8.262


  8 in total

1.  Reversal of delirium induced by tricyclic antidepressant drugs with physostigmine.

Authors:  J F Heiser; D E Wilbert
Journal:  Am J Psychiatry       Date:  1974-11       Impact factor: 18.112

2.  Doxepin overdose. Success with physostigmine and failure with neostigmine in reversing toxicity.

Authors:  P A Janson; J B Watt; J A Hermos
Journal:  JAMA       Date:  1977-06-13       Impact factor: 56.272

3.  Tricyclic-antidepressant-induced delirium and plasma drug concentration.

Authors:  S H Preskorn; S Simpson
Journal:  Am J Psychiatry       Date:  1982-06       Impact factor: 18.112

4.  Tricyclic antidepressants: plasma levels and clinical findings in overdose.

Authors:  D N Bailey; C Van Dyke; R A Langou; P I Jatlow
Journal:  Am J Psychiatry       Date:  1978-11       Impact factor: 18.112

5.  Letter: Reversal by physostigmine of clozapine-induced delirium.

Authors:  P Schuster; E Gabriel; B Küfferle; M Karobath
Journal:  Lancet       Date:  1976-01-03       Impact factor: 79.321

6.  Amitriptyline plasma levels and therapeutic response.

Authors:  V E Ziegler; B T Co; J R Taylor; P J Clayton; J T Biggs
Journal:  Clin Pharmacol Ther       Date:  1976-06       Impact factor: 6.875

7.  Tricyclic antidepressants. Prolonged plasma levels after overdose.

Authors:  D G Spiker; J T Biggs
Journal:  JAMA       Date:  1976-10-11       Impact factor: 56.272

8.  Tricyclic antidepressant overdose: clinical presentation and plasma levels.

Authors:  D G Spiker; A N Weiss; S S Chang; J F Ruwitch; J T Biggs
Journal:  Clin Pharmacol Ther       Date:  1975-11       Impact factor: 6.875
  8 in total
  1 in total

1.  Physiologically based pharmacokinetic-quantitative systems toxicology and safety (PBPK-QSTS) modeling approach applied to predict the variability of amitriptyline pharmacokinetics and cardiac safety in populations and in individuals.

Authors:  Zofia Tylutki; Aleksander Mendyk; Sebastian Polak
Journal:  J Pharmacokinet Pharmacodyn       Date:  2018-06-25       Impact factor: 2.745
  1 in total

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