Literature DB >> 6639040

Comparison of cytotoxicity and thin-layer chromatography methods for detection of mycotoxins.

J Robb, M Norval.   

Abstract

Thirty-three standard mycotoxins were assayed by thin-layer chromatography and by cytotoxicity in HEp-2 and Chang cells. Various levels of detection were found. The cytotoxicity test was significantly more sensitive than thin-layer chromatography for the trichothecenes and should be useful for screening extracts from animal feedstuffs for the presence of unknown mycotoxins.

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Year:  1983        PMID： 6639040      PMCID： PMC239494          DOI： 10.1128/aem.46.4.948-950.1983

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  7 in total

1.  Effect of aflatoxin B and rubratoxin B on bacteriophage and rabbit cornea cells.

Authors:  A W Hayes
Journal:  Bull Environ Contam Toxicol       Date:  1976-06       Impact factor: 2.151

2.  Screening tests using HeLa cells and mice for detection of mycotoxin-producing fungi isolated from foodstuffs.

Authors:  M Saito; K Otsubo; M Umeda; M Enomoto; H Kurata
Journal:  Jpn J Exp Med       Date:  1971-02

3.  [A cell-culture assay for the detection of mycotoxins. I. Investigations with pure toxins (author's transl)].

Authors:  A Lompe; K E von Milczewski
Journal:  Z Lebensm Unters Forsch       Date:  1979-10

4.  Mycotoxins in animal feedstuffs: sensitive thin layer chromatographic detection of aflatoxin, ochratoxin A, sterigmatocystin, zearalenone, and T-2 toxin.

Authors:  D S Patterson; B A Roberts
Journal:  J Assoc Off Anal Chem       Date:  1979-11

5.  Brine shrimp (Artemia salina L.) larvae as a screening system for fungal toxins.

Authors:  J Harwig; P M Scott
Journal:  Appl Microbiol       Date:  1971-06

6.  Toxicity testing in vitro. I. The effects of delta 9-tetrahydrocannabinol and aflatoxin B1 on the growth of cultured human fibroblasts.

Authors:  J T Cooper; S Goldstein
Journal:  Can J Physiol Pharmacol       Date:  1976-08       Impact factor: 2.273

7.  Association of toxin-producing fungi with disease in broilers.

Authors:  J Robb; K S Kirkpatrick; M Norval
Journal:  Vet Rec       Date:  1982-10-23       Impact factor: 2.695
  7 in total
  6 in total

1.  The cytotoxicity of T-2 toxin and related 12,13-epoxytrichothecenes to Adriamycin-sensitive and -resistant P388 leukemia cells.

Authors:  A Ramu; B Yagen; N Ramu
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

2.  Cytotoxicity of four trichothecenes evaluated by three colorimetric bioassays.

Authors:  J Widestrand; T Lundh; H Pettersson; J E Lindberg
Journal:  Mycopathologia       Date:  1999       Impact factor: 2.574

3.  Highly sensitive protein translation assay for trichothecene toxicity in airborne particulates: comparison with cytotoxicity assays.

Authors:  I Yike; T Allan; W G Sorenson; D G Dearborn
Journal:  Appl Environ Microbiol       Date:  1999-01       Impact factor: 4.792

4.  Toxicity of epoxy trichothecenes in cultured mammalian cells.

Authors:  K von Milczewski
Journal:  Mycotoxin Res       Date:  1987-09       Impact factor: 3.833

5.  Cytotoxicity of mycotoxins evaluated by the MTT-cell culture assay.

Authors:  M Hanelt; M Gareis; B Kollarczik
Journal:  Mycopathologia       Date:  1994-12       Impact factor: 2.574

6.  The use of isolated human lymphocytes in mycotoxin cytotoxicity testing.

Authors:  Pholo W Maenetje; Neil De Villiers; Mike F Dutton
Journal:  Int J Mol Sci       Date:  2008-08-25       Impact factor: 6.208
  6 in total

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