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Literature DB >> 6639002

In vitro activity of rodogyl against putative periodontopathic bacteria.

Abstract

The minimal inhibitory concentrations of Rodogyl (composite tablet of metronidazole and spiramycin), metronidazole-spiramycin mixture, spiramycin, metronidazole, and tetracycline were determined for selected putative periodontopathic microorganisms. Rodogyl was active against almost all strains, including Bacteroides species and the anaerobic spirochetes. Synergism of the component drugs in the Rodogyl combination was noted against Propionibacterium species. Spiramycin activity against Actinomyces species was enhanced in the presence of metronidazole.

Entities: Chemical

Mesh：

Substances：

Year: 1983 PMID： 6639002 PMCID： PMC185344 DOI： 10.1128/AAC.24.3.445

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

13 in total

1. Anti-infectives.

Authors: A A Brown
Journal: Ont Dent Date: 1976-12

2. Evaluation of spiramycin as a therapeutic agent for elimination of nasopharyngeal pathogens. Possible use of spiramycin for middle ear infections and for gonococcal and meningococcal nasopharyngeal carriage.

Authors: C Kamme; G Kahlmeter; A Melander
Journal: Scand J Infect Dis Date: 1978

3. Relative distribution of bacteria at clinically healthy and periodontally diseased sites in humans.

Authors: M A Listgarten; L Helldén
Journal: J Clin Periodontol Date: 1978-05 Impact factor: 8.728

4. [Metronidazole-spiramycin combination. In situ concentrations and synergism compared with the minimal inhibitory concentration of the buccal flora].

Authors: J Laufer; H Mignon; D Videau
Journal: Rev Stomatol Chir Maxillofac Date: 1974 Jul-Aug

9. Positive correlation between the proportions of subgingival spirochetes and motile bacteria and susceptibility of human subjects to periodontal deterioration.

Authors: M A Listgarten; S Levin
Journal: J Clin Periodontol Date: 1981-04 Impact factor: 8.728

10. Treatment of periodontal infections due to anaerobic bacteria with short-term treatment with metronidazole.

Authors: W J Loesche; S A Syed; E C Morrison; B Laughon; N S Grossman
Journal: J Clin Periodontol Date: 1981-02 Impact factor: 8.728

1 in total

1. Effect of Tetracycline Hydrochloride and Spiramycin Sub Gingival Irrigation with Pulsated Jet Irrigator in Chronic Periodontitis Patients: A Clinical Study.

Authors: P L Ravishankar; K Venugopal; Purnima Nadkerny
Journal: J Int Oral Health Date: 2015-07

1 in total

In vitro activity of rodogyl against putative periodontopathic bacteria.

1. Anti-infectives.

2. Evaluation of spiramycin as a therapeutic agent for elimination of nasopharyngeal pathogens. Possible use of spiramycin for middle ear infections and for gonococcal and meningococcal nasopharyngeal carriage.

3. Relative distribution of bacteria at clinically healthy and periodontally diseased sites in humans.

4. [Metronidazole-spiramycin combination. In situ concentrations and synergism compared with the minimal inhibitory concentration of the buccal flora].

5. Antibiotic therapy in periodontal disease.

6. Bacteroides species and gelatinase-producers in periodontal disease.

Review 7. Antibiotics in the treatment of human periodontal diseases.

8. Studies of the predominant cultivable microbiota of early periodontitis.

9. Positive correlation between the proportions of subgingival spirochetes and motile bacteria and susceptibility of human subjects to periodontal deterioration.

10. Treatment of periodontal infections due to anaerobic bacteria with short-term treatment with metronidazole.

1. Effect of Tetracycline Hydrochloride and Spiramycin Sub Gingival Irrigation with Pulsated Jet Irrigator in Chronic Periodontitis Patients: A Clinical Study.