Literature DB >> 6639000

Effect of N, N'-dicyclohexylcarbodiimide and nigericin on Staphylococcus aureus susceptibility to gentamicin.

L J Mandel, E S Eisenberg, N J Simkin, M H Miller.   

Abstract

The abilities of the H+-ATPase inhibitor N, N'-dicyclohexylcarbodiimide and the antibiotic ionophore nigericin to enhance the bactericidal effect of subinhibitory concentrations of gentamicin in two strains of Staphylococcus aureus were studied. Each compound significantly increased both gentamicin uptake and killing. The use of agents which alter the plasma membrane energy state is a novel approach to enhance the activity of conventional antibiotics.

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Year:  1983        PMID： 6639000      PMCID： PMC185342          DOI： 10.1128/AAC.24.3.440

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  Matrix protein from Escherichia coli outer membranes forms voltage-controlled channels in lipid bilayers.

Authors:  H Schindler; J P Rosenbusch
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

Review 2.  Polyether antibiotics: versatile carboxylic acid ionophores produced by Streptomyces.

Authors:  J W Westley
Journal:  Adv Appl Microbiol       Date:  1977       Impact factor: 5.086

Review 3.  The mechanism of the irreversible antimicrobial effects of penicillins: how the beta-lactam antibiotics kill and lyse bacteria.

Authors:  A Tomasz
Journal:  Annu Rev Microbiol       Date:  1979       Impact factor: 15.500

4.  Membrane potential in anaerobically growing Staphylococcus aureus and its relationship to gentamicin uptake.

Authors:  S M Mates; L Patel; H R Kaback; M H Miller
Journal:  Antimicrob Agents Chemother       Date:  1983-04       Impact factor: 5.191

5.  Energy is required for maturation of exported proteins in Escherichia coli.

Authors:  H G Enequist; T R Hirst; S Harayama; S J Hardy; L L Randall
Journal:  Eur J Biochem       Date:  1981-05-15

6.  Studies on antibiotic syngerism against enterococci. II. Effect of various antibiotics on the uptake of 14 C-labeled streptomycin by enterococci.

Authors:  R C Moellering; A N Weinberg
Journal:  J Clin Invest       Date:  1971-12       Impact factor: 14.808

7.  Single and combination antibiotic therapy of Staphylococcus aureus experimental endocarditis: emergence of gentamicin-resistant mutants.

Authors:  M H Miller; M A Wexler; N H Steigbigel
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191

8.  Membrane potential and gentamicin uptake in Staphylococcus aureus.

Authors:  S M Mates; E S Eisenberg; L J Mandel; L Patel; H R Kaback; M H Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205

9.  Gentamicin uptake in wild-type and aminoglycoside-resistant small-colony mutants of Staphylococcus aureus.

Authors:  M H Miller; S C Edberg; L J Mandel; C F Behar; N H Steigbigel
Journal:  Antimicrob Agents Chemother       Date:  1980-11       Impact factor: 5.191

10.  Active uptake of tetracycline by membrane vesicles from susceptible Escherichia coli.

Authors:  L M McMurry; J C Cullinane; R E Petrucci; S B Levy
Journal:  Antimicrob Agents Chemother       Date:  1981-09       Impact factor: 5.191
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  8 in total

1.  Increased susceptibility of transfected prokaryotic and eukaryotic cells to antibiotic selection.

Authors:  F A Asselbergs; P van Someren
Journal:  Antimicrob Agents Chemother       Date:  1992-08       Impact factor: 5.191

2.  Acquired gentamicin resistance by permeability impairment in Enterococcus faecalis.

Authors:  Elisabeth Aslangul; Laurent Massias; Alain Meulemans; Françoise Chau; Antoine Andremont; Patrice Courvalin; Bruno Fantin; Raymond Ruimy
Journal:  Antimicrob Agents Chemother       Date:  2006-11       Impact factor: 5.191

Review 3.  Bacterial uptake of aminoglycoside antibiotics.

Authors:  H W Taber; J P Mueller; P F Miller; A S Arrow
Journal:  Microbiol Rev       Date:  1987-12

4.  Early effects of beta-lactams on aminoglycoside uptake, bactericidal rates, and turbidimetrically measured growth inhibition in Pseudomonas aeruginosa.

Authors:  M H Miller; S A Feinstein; R T Chow
Journal:  Antimicrob Agents Chemother       Date:  1987-01       Impact factor: 5.191

5.  Penicillin-induced effects on streptomycin uptake and early bactericidal activity differ in viridans group and enterococcal streptococci.

Authors:  M H Miller; M A el-Sokkary; S A Feinstein; F D Lowy
Journal:  Antimicrob Agents Chemother       Date:  1986-11       Impact factor: 5.191

6.  Tobramycin uptake in Escherichia coli membrane vesicles.

Authors:  I M Leviton; H S Fraimow; N Carrasco; T J Dougherty; M H Miller
Journal:  Antimicrob Agents Chemother       Date:  1995-02       Impact factor: 5.191

7.  Gentamicin uptake in Staphylococcus aureus possessing plasmid-encoded, aminoglycoside-modifying enzymes.

Authors:  L J Mandel; E Murphy; N H Steigbigel; M H Miller
Journal:  Antimicrob Agents Chemother       Date:  1984-10       Impact factor: 5.191

8.  Adaptive responses of Bacillus cereus ATCC14579 cells upon exposure to acid conditions involve ATPase activity to maintain their internal pH.

Authors:  Khadidja Senouci-Rezkallah; Michel P Jobin; Philippe Schmitt
Journal:  Microbiologyopen       Date:  2015-03-05       Impact factor: 3.139
  8 in total

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