Literature DB >> 663667

Genomic masking of nondefective recombinant murine leukemia virus in Moloney virus stocks.

P J Fischinger, C S Blevins, N M Dunlop.   

Abstract

HIX virus cloned from Moloney leukemia virus stocks is a nondefective, leukemogenic, and amphotropic murine oncornavirus with a recombinant-type major glycoprotein. Although Moloney leukemia virus stocks generally contain little or no free amphotropic virus, dilution analysis of several virus stocks and the examination of virus progeny from individual foci revealed that HIX virus is present and functionally coated with ecotropic Moloney virus envelopes. Because most mice have serum factors that inactivate recombinant viruses, masking may represent a general survival mechanism for HIX as well as other analogous recombinant viruses.

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Year:  1978        PMID： 663667     DOI： 10.1126/science.663667

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  16 in total

1.  Isolation of host-range variants of mouse mammary tumor viruses that efficiently infect cells in vitro.

Authors:  D K Howard; J Schlom
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

2.  Ping-pong amplification of a retroviral vector achieves high-level gene expression: human growth hormone production.

Authors:  S L Kozak; D Kabat
Journal:  J Virol       Date:  1990-07       Impact factor: 5.103

3.  Selective host range restriction of goat cells for recombinant murine leukemia virus and feline leukemia virus type A.

Authors:  P J Fischinger; H J Thiel; C S Blevins; N M Dunlop
Journal:  J Virol       Date:  1981-09       Impact factor: 5.103

4.  Biological, chemical, and immunological studies of Rauscher ecotropic and mink cell focus-forming viruses from JLS-V9 cells.

Authors:  A Schultz; A Rein; L Henderson; S Oroszlan
Journal:  J Virol       Date:  1983-03       Impact factor: 5.103

5.  Leukemogenesis by Gross passage A murine leukemia virus: expression of viruses with recombinant env genes in transformed cells.

Authors:  N G Famulari; C F Koehne; P V O'Donnell
Journal:  Proc Natl Acad Sci U S A       Date:  1982-06       Impact factor: 11.205

6.  A multistep process of leukemogenesis in Moloney murine leukemia virus-infected mice that is modulated by retroviral pseudotyping and interference.

Authors:  M Lavignon; L Evans
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

7.  Genomic masking and rescue of dual-tropic murine leukemia viruses: role of pseudotype virions in viral lymphomagenesis.

Authors:  M Haas; V Patch
Journal:  J Virol       Date:  1980-09       Impact factor: 5.103

8.  Protection from spontaneous lymphoma development in SJL/J(v+) mice neonatally injected with dualtropic SJL-151 virus.

Authors:  A De Rossi; E D'Andrea; G Biasi; D Collavo; L Chieco-Bianchi
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205

9.  Mobilization of endogenous retroviruses in mice after infection with an exogenous retrovirus.

Authors:  Leonard H Evans; A S M Alamgir; Nick Owens; Nick Weber; Kimmo Virtaneva; Kent Barbian; Amenah Babar; Frank Malik; Kyle Rosenke
Journal:  J Virol       Date:  2008-12-30       Impact factor: 5.103

10.  Glycoprotein encoded by the Friend spleen focus-forming virus.

Authors:  S Dresler; M Ruta; M J Murray; D Kabat
Journal:  J Virol       Date:  1979-05       Impact factor: 5.103
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