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Literature DB >> 663662

Brain edema: induction in cortical slices by polyunsaturated fatty acids.

Abstract

The presence of polyunsaturated and saturated fatty acids in leukocytic membranes prompted study of their possible role in the induction of brain edema. Polyunsaturated fatty acids including sodium arachidonate, sodium linoleate, sodium linolenate, and docasahexaenoic acids induced edma in slices of rat brain cortex. This cellular edema was specific, since neither saturated fatty acids nor a fatty acid containing a single double bond had such effect.

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Year: 1978 PMID： 663662 DOI： 10.1126/science.663662

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

29 in total

Review 1. Neonatal brain infections.

Authors: Jacques F Schneider
Journal: Pediatr Radiol Date: 2011-04-27

2. Lipid peroxides are generated by the fetal rat brain after episodes of global ischemia in utero.

Authors: S Glozman; E Yavin
Journal: Neurochem Res Date: 1997-02 Impact factor: 3.996

3. The contribution of arachidonic acid to the aetiology and pathophysiology of focal brain oedema; studies using an infusion oedema model.

Authors: I R Whittle; I R Piper; J D Miller
Journal: Acta Neurochir (Wien) Date: 1991 Impact factor: 2.216

10. Reduction of lipoxidative load by secretory phospholipase A2 inhibition protects against neurovascular injury following experimental stroke in rat.

Authors: Md Nasrul Hoda; Inderjit Singh; Avtar K Singh; Mushfiquddin Khan
Journal: J Neuroinflammation Date: 2009-08-13 Impact factor: 8.322

Brain edema: induction in cortical slices by polyunsaturated fatty acids.

Review 1. Neonatal brain infections.

2. Lipid peroxides are generated by the fetal rat brain after episodes of global ischemia in utero.

3. The contribution of arachidonic acid to the aetiology and pathophysiology of focal brain oedema; studies using an infusion oedema model.

4. Permeability and vasomotor response of cerebral vessels during exposure to arachidonic acid.

Review 5. Current concepts in bacterial meningitis.

6. Superoxide dismutase does not prevent delayed hypoperfusion after incomplete cerebral ischaemia in the rat.

Review 7. Pathogenesis and pathophysiology of bacterial meningitis.

8. Arachidonic acid-induced swelling in incubated rat brain cortical slices. Effect of bovine serum albumin.

Review 9. Mammalian lipoxygenases and their biological relevance.

10. Reduction of lipoxidative load by secretory phospholipase A2 inhibition protects against neurovascular injury following experimental stroke in rat.