Literature DB >> 6636343

Central nervous system reactions during heliox and trimix dives to 51 ATA, DEEP EX 81.

R Vaernes, D Hammerborg, B Ellertsen, R Peterson, S Tønjum.   

Abstract

UNLABELLED: Two groups of divers were compressed to 500 msw with heliox (n = 3) and trimix (n = 3). They were followed with repeated neuropsychological and neurological tests during compression, at stable intermediate depths, and at 500 msw. For the heliox group there was a marked increase in tremor and EEG slow waves and reduction in handgrip strength. For the trimix group the tremor increase did not occur, but the EEG changes were the same as in the heliox group. On motor tests only the trimix group showed impaired finger dexterity and manual dexterity. The same occurred for fine visuomotor coordination, but both groups had increased intentional tremor. On cognitive tests the same difference occurred. The trimix group was markedly impaired in reasoning and long-term memory, while only a mild impairment was found in the heliox group. Dizziness and other symptoms of high pressure nervous syndrome (HPNS) occurred in both groups.
CONCLUSION: There were marked HPNS effects during compression for both groups. Only tremor was inhibited by the nitrogen. In addition, the trimix group was impaired because of nitrogen narcosis. These data indicated that 10% nitrogen did not inhibit HPNS effects during compression to 500 msw, but the considerable differences between subjects shows that susceptibility to compression must be an important area for future research.

Entities:  

Mesh:

Substances:

Year:  1983        PMID: 6636343

Source DB:  PubMed          Journal:  Undersea Biomed Res        ISSN: 0093-5387


  3 in total

1.  Alterations in brain monoamine neurotransmitter release at high pressure.

Authors:  S C Gilman; J S Colton; A J Dutka
Journal:  Exp Brain Res       Date:  1989       Impact factor: 1.972

2.  Reversible GABAergic dysfunction involved in hippocampal hyperactivity predicts early-stage Alzheimer disease in a mouse model.

Authors:  Yang Li; Ke Zhu; Ning Li; Xiaotong Wang; Xuansheng Xiao; Linying Li; Lijuan Li; Ying He; Jinglan Zhang; Jiaoyang Wo; Yanqiu Cui; Haixia Huang; Jianliang Zhang; Wei Wang; Xiaomin Wang; Yan Zheng
Journal:  Alzheimers Res Ther       Date:  2021-06-14       Impact factor: 6.982

3.  Evaluation of Divers' Neuropsychometric Effectiveness and High-Pressure Neurological Syndrome via Computerized Test Battery Package and Questionnaires in Operational Setting.

Authors:  Simin Berenji Ardestani; Costantino Balestra; Elena V Bouzinova; Øyvind Loennechen; Michael Pedersen
Journal:  Front Physiol       Date:  2019-11-08       Impact factor: 4.566

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.