Literature DB >> 6634910

[Synthesis and analgesic effect of 2-aryliminomethylquinolines].

V Hagen, B Dove, E Morgenstern, D Labes, E Göres, G Tomaschewski, G Geisler, C Franke.   

Abstract

2-Aryliminomethylquinolines were synthesized by the condensation of quinoline-2-carbaldehyde with the corresponding anilines. The compounds were evaluated for analgesic activity using the acetic acid writhing test. Some of them showed significant inhibition of the writhing syndrome. The most potent compound 3b was approximately as active as aminophenazone in the writhing and the hot-plate method.

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Year:  1983        PMID: 6634910

Source DB:  PubMed          Journal:  Pharmazie        ISSN: 0031-7144            Impact factor:   1.267


  1 in total

1.  2-[(E)-4-Quinolylmethyl-ideneamino]-phenol.

Authors:  Sema Öztürk Yıldırım; Mehmet Akkurt; Mustafa Kemal Gümüş; Mevlüde Canlıca; Seniz Kaban; Vickie McKee
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-10-22
  1 in total

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