Literature DB >> 6634885

Cardiovascular and plasma prolactin responses to stereoisomers of phencyclidine.

M A Bayorh, D Lozovsky, K C Rice, T R Burke, I J Kopin.   

Abstract

The effect of phencyclidine (PCP) and dextro- and levorotatory isomers of its derivatives 1-(1-phenylcyclo-hexyl)-3-methylpiperidine [(+)-PCMP and (-)-PCMP] (5 mg/kg, SC) on blood pressure (BP), heart rate (HR) and plasma prolactin (PRL) were examined. PCP and (+)-PCMP but not (-)-PCMP increased BP and HR and suppressed plasma PRL.

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Year:  1983        PMID: 6634885     DOI: 10.1016/0091-3057(83)90066-7

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN: 0091-3057            Impact factor:   3.533


  2 in total

1.  Nonpsychotropic cannabinoid acts as a functional N-methyl-D-aspartate receptor blocker.

Authors:  J J Feigenbaum; F Bergmann; S A Richmond; R Mechoulam; V Nadler; Y Kloog; M Sokolovsky
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

Review 2.  Phencyclidine. Physiological actions, interactions with excitatory amino acids and endogenous ligands.

Authors:  P C Contreras; J B Monahan; T H Lanthorn; L M Pullan; D A DiMaggio; G E Handelmann; N M Gray; T L O'Donohue
Journal:  Mol Neurobiol       Date:  1987       Impact factor: 5.590

  2 in total

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