| Literature DB >> 6634542 |
M D Morgan, D J Rainford, C D Pusey, A M Robins-Cherry, J G Henry.
Abstract
Quinine poisoning is rare but serious. Attempts at treatment by active removal have proved unsuccessful because of its high degree of protein binding. We describe two cases of non-accidental overdose of quinine (19.5 g and 15 g) with potentially fatal serum quinine levels. Both patients were treated by 2 periods of charcoal haemoperfusion during which quinine clearances of up to 125 ml/min were obtained. Both patients recovered, though one had some residual visual disturbance. We suggest that in cases of quinine poisoning, charcoal haemoperfusion may be a safe and effective method of drug removal, to be used with stellate ganglion block.Entities:
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Year: 1983 PMID： 6634542 PMCID： PMC2417512 DOI： 10.1136/pgmj.59.692.365
Source DB: PubMed Journal: Postgrad Med J ISSN： 0032-5473 Impact factor: 2.401