| Literature DB >> 6634474 |
O Gaffori, M Geffard, J M van Ree.
Abstract
The effect of subcutaneously injected DT gamma E (beta-endorphin, (beta E)2-17) on the pineal melatonin level was compared with that of closely related peptides and the neuroleptic drug haloperidol. As found previously, DT gamma E (3 ng/rat and 300 ng/rat) increased the melatonin levels. Similar doses of DT alpha E (beta E 2-16), DT beta E (beta E 2-31), gamma E (beta E 1-17), alpha E (beta E 1-16) and beta E failed to significantly change the melatonin levels in both the dark and the light phase. Haloperidol in a dose of 300 ng/rat exhibited a similar effect as DT gamma E.Entities:
Mesh：
Substances：
Year: 1983 PMID： 6634474 DOI： 10.1016/0196-9781(83)90152-3
Source DB: PubMed Journal: Peptides ISSN： 0196-9781 Impact factor: 3.750