| Literature DB >> 6632798 |
R C Meatherall, D R Guay, J L Chalmers, J R Keenan.
Abstract
A death attributed to self administration of toxic amounts of clomipramine is reported. Analysis of post mortem blood showed clomipramine at a concentration of 540 ng/mL and its active metabolite, N-desmethylclomipramine, at a concentration of 580 ng/mL. The corresponding concentrations of the parent compound and metabolite in the urine were only 350 ng/mL and 700 ng/mL, respectively. These blood results are construed to represent minimum lethal concentrations for the two combined compounds.Entities:
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Year: 1983 PMID： 6632798 DOI： 10.1093/jat/7.4.168
Source DB: PubMed Journal: J Anal Toxicol ISSN： 0146-4760 Impact factor: 3.367