Literature DB >> 6631920

Antidiabetic activity of some 1-substituted 3,5-dimethylpyrazoles.

R Soliman, S A Darwish.   

Abstract

Several new 1-substituted 3,5-dimethylpyrazoles were prepared for testing as hypoglycemic agents. A number of these containing para-substituted 1-carbonylphenylurea and para-substituted 1-carbamoylbenzenesulfonylurea derivatives were found to possess potent hypoglycemic activity.

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Year:  1983        PMID： 6631920     DOI： 10.1021/jm00365a023

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


  2 in total

1.  Room temperature ICl-induced dehydration/iodination of 1-acyl-5-hydroxy-4,5-dihydro-1H-pyrazoles. a selective route to substituted 1-acyl-4-iodo-1H-pyrazoles.

Authors:  Jesse P Waldo; Saurabh Mehta; Richard C Larock
Journal:  J Org Chem       Date:  2008-07-30       Impact factor: 4.354

2.  Para-Aminobenzohydrazide Derivatives as Fatty Acid Amide Hydrolase Inhibitors: Design, Synthesis and Biological Evaluation.

Authors:  Anna Sedaghat; Elham Rezaee; Omid Hosseini; Sayyed Abbas Tabatabai
Journal:  Iran J Pharm Res       Date:  2020       Impact factor: 1.696
  2 in total

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