Literature DB >> 6631445

Supernumerary lactate dehydrogenase isozymes in human gliomas.

H Egami, I Takeshita, M Fukui, K Kitamura.   

Abstract

Supernumerary bands in agarose gel electrophoresis of lactate dehydrogenase (LDH) were frequently observed in extracts of human gliomas. The supernumerary fractions which migrated cathodic to LDH-2 and/or cathodic to LDH-3 were designated LDH-2' and LDH-3'. These extra bands were clearly seen in certain gliomas and less distinctly in others, being more frequent in primitive or undifferentiated tumours. The extra bands seen in gliomas differ from the LDH-X of the testis, but LDH-2' seemed correspond to LDH-Z in placenta, hydatidiform mole, and choriocarcinoma. These sub-bands are interpreted as being produced by gliomas and as oncofetal enzymes.

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Year:  1983        PMID: 6631445     DOI: 10.1016/0022-510x(83)90049-7

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN: 0022-510X            Impact factor:   3.181


  3 in total

1.  Gossypol treatment of recurrent adult malignant gliomas.

Authors:  P Bushunow; M M Reidenberg; J Wasenko; J Winfield; B Lorenzo; S Lemke; B Himpler; R Corona; T Coyle
Journal:  J Neurooncol       Date:  1999-05       Impact factor: 4.130

2.  LDH isoenzymes in cerebrospinal fluid in various brain tumours.

Authors:  Y Lampl; Y Paniri; Y Eshel; I Sarova-Pinhas
Journal:  J Neurol Neurosurg Psychiatry       Date:  1990-08       Impact factor: 10.154

3.  Contrary effect of lactic acid on expression of neuron-specific enolase and glial fibrillary acidic protein in human glioma cells.

Authors:  I Takeshita; H Sawa; T Nakamura; M Kuramitsu; K Kitamura; M Fukui
Journal:  Acta Neuropathol       Date:  1990       Impact factor: 17.088

  3 in total

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