Literature DB >> 6631315

Growth of 9.5-day rat embryos in human serum.

M Gupta, F Beck.   

Abstract

Rat embryos were explanted at 9.5 days and cultured for 48 h in human serum supplemented with glucose. The embryos were anaemic and frequently malformed. The haemoglobin and DNA content of these embryos was less than those grown in pure rat serum. Addition of 10% rat serum improved the embryonic growth as well as the haemoglobin and DNA content. This suggests that rat serum provides essential growth factors required by the embryos which are not present in human serum.

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Year:  1983        PMID: 6631315

Source DB:  PubMed          Journal:  J Embryol Exp Morphol        ISSN: 0022-0752


  4 in total

1.  The effect of macromolecular rat serum fractions on conceptuses cultured in human serum: role of transferrin.

Authors:  A P Gulamhusein; M K Pratten; C A Williams; F Beck
Journal:  J Anat       Date:  1990-02       Impact factor: 2.610

2.  Comparative enzyme histochemical study on the visceral yolk sac endoderm in the rat in vivo and in vitro.

Authors:  A Miki; P Kugler
Journal:  Histochemistry       Date:  1984

3.  Preimplantation mouse embryos cultured in mouse, rat and human sera: differentiation and sister chromatid exchange.

Authors:  C Krüger; R Vogel; H Spielmann
Journal:  Experientia       Date:  1985-12-15

4.  Human serum as a culture medium for rat embryos.

Authors:  C E Steele
Journal:  Experientia       Date:  1985-12-15
  4 in total

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