Literature DB >> 6628681

Characterization of oligosaccharides from the urine of loco-intoxicated sheep.

S Sadeh, C D Warren, P F Daniel, B Bugge, L F James, R W Jeanloz.   

Abstract

Two major oligosaccharides were isolated by preparative HPLC from the urine of a locoweed-fed sheep. Analysis by gas-liquid chromatography and mass-spectrometry indicated compositions of (Man)4(GlcNAc)2 and (Man)5(GlcNAc)2, respectively. Structures were determined by digestion with alpha-D-mannosidase and endo-beta-N-acetylglucosaminidases D and H, and comparison of the products by HPLC with synthetic standards, and oligosaccharides isolated from human mannosidosis urine. Incubation with an exo-beta-N-acetylglucosaminidase was without effect.

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Year:  1983        PMID: 6628681     DOI: 10.1016/0014-5793(83)81173-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  4 in total

1.  Properties of baby-hamster kidney (BHK) cells treated with Swainsonine, an inhibitor of glycoprotein processing. Comparison with ricin-resistant BHK-cell mutants.

Authors:  L Foddy; J Feeney; R C Hughes
Journal:  Biochem J       Date:  1986-02-01       Impact factor: 3.857

2.  Glycoprotein metabolism in normal and beta-mannosidase-deficient cultured goat skin fibroblasts.

Authors:  L W Hancock; M Z Jones; G Dawson
Journal:  Biochem J       Date:  1986-02-15       Impact factor: 3.857

3.  Swainsonine-induced oligosaccharide excretion in sheep. Time-dependent changes in the oligosaccharide profile.

Authors:  P F Daniel; C D Warren; L F James
Journal:  Biochem J       Date:  1984-08-01       Impact factor: 3.857

4.  Structural analysis of the major urinary oligosaccharides in feline alpha-mannosidosis.

Authors:  D Abraham; P Daniel; A Dell; J Oates; R Sidebotham; B Winchester
Journal:  Biochem J       Date:  1986-02-01       Impact factor: 3.857

  4 in total

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