Literature DB >> 6628153

Adenocarcinoma of the rectum arising in a hamartomatous polyp in a patient with Peutz-Jeghers syndrome.

L J Miller, L G Bartholomew, R R Dozois, D C Dahlin.   

Abstract

The malignant potential of the hamartomatous polyps in Peutz-Jeghers syndrome has been debated. Although this is a very rare event, these polyps can undergo carcinomatous transformation, as demonstrated by this report of a 37-year-old man with well-documented Peutz-Jeghers syndrome who developed an invasive grade 2 adenocarcinoma on the surface of a hamartomatous polyp in the rectum.

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Year:  1983        PMID: 6628153     DOI: 10.1007/bf01311735

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  21 in total

1.  Malignant degeneration and metastasis in Peutz-Jeghers syndrome.

Authors:  J L ACHORD; H D PROCTOR
Journal:  Arch Intern Med       Date:  1963-04

2.  PEUTZ-JEGHERS SYNDROME WITH METASTASIZING DUODENAL CARCINOMA.

Authors:  J P WILLIAMS; A KNUDSEN
Journal:  Gut       Date:  1965-04       Impact factor: 23.059

3.  [Generalized intestinal polyposis with melanoplakia (Peutz-Jeghers syndrome)].

Authors:  B HERMANN; A SARO
Journal:  Orv Hetil       Date:  1961-01-15       Impact factor: 0.540

Review 4.  The Peutz-Jeghers syndrome. Is there a predisposition to the development of intestinal malignancy?

Authors:  R R Dozois; E S Judd; D C Dahlin; L G Bartholomew
Journal:  Arch Surg       Date:  1969-04

5.  [A case of Peutz-Jeghers syndrome with malignant degeneration].

Authors:  U Gasser; A Arquint
Journal:  Schweiz Med Wochenschr       Date:  1969-12-27

6.  [Familial polyposis of Peutz-Jeghers type with malignant degeneration].

Authors:  G Moretti; C Bozic; N Genton
Journal:  Ann Chir Infant       Date:  1969 May-Jun

7.  Peutzjeghers syndrome with carcinoma of the duodenum and jejunum.

Authors:  K W Warren; G A Kune; J K Poulantzas
Journal:  Lahey Clin Found Bull       Date:  1965

8.  Peutz-Jeghers syndrome with intestinal carcinoma: report of the association in one family.

Authors:  S D Hsu; P Zaharopoulos; J T May; J J Costanzi
Journal:  Cancer       Date:  1979-10       Impact factor: 6.860

9.  Extensive metastases in Peutz-Jeghers syndrome.

Authors:  U Y Ryo; S K Roh; R B Balkin; L B Siedband; G W Sobel; S M Pinsky
Journal:  JAMA       Date:  1978-05-26       Impact factor: 56.272

10.  Adenomatous and carcinomatous changes in hamartomatous polyps of the small intestine (Peutz-Jeghers syndrome): report of a case and review of the literature.

Authors:  K H Perzin; M F Bridge
Journal:  Cancer       Date:  1982-03-01       Impact factor: 6.860

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  8 in total

1.  Co-occurrence of an adenoma malignum and an endocervical-type adenocarcinoma of the uterine cervix in a woman with Peutz-Jeghers syndrome.

Authors:  Yu-Jin Koo; Ji-Eun Lee; Sung-Ran Hong; Yong-Soon Kwon
Journal:  J Gynecol Oncol       Date:  2010-09-28       Impact factor: 4.401

2.  Intussusception in the adult: an unsuspected case of Peutz-Jeghers syndrome with review of the literature.

Authors:  Jason D Fraser; Steven E Briggs; Shawn D St Peter; Giovanni De Petris; Jacques Heppell
Journal:  Fam Cancer       Date:  2008-08-23       Impact factor: 2.375

3.  Peutz-Jeghers syndrome: a study of long-term surgical morbidity and causes of mortality.

Authors:  Y Nancy You; Bruce G Wolff; Lisa A Boardman; Douglas L Riegert-Johnson; Rui Qin
Journal:  Fam Cancer       Date:  2010-12       Impact factor: 2.375

4.  Peutz-Jeghers syndrome associated with adenocarcinoma of the cecum and focal carcinomas in hamartomatous polyps of the colon: a case report.

Authors:  K Niimi; H Tomoda; M Furusawa; I Hayashi; Y Okumura
Journal:  Jpn J Surg       Date:  1991-03

Review 5.  [Peutz-Jeghers syndrome. Cases at the Mannheim clinic over 25 years].

Authors:  S Loff; L Wessel; H Wirth; B C Manegold; H Pilcher; K L Waag
Journal:  Langenbecks Arch Chir       Date:  1995

6.  Polyps in children.

Authors:  Vincent R Adolph; Kathryn Bernabe
Journal:  Clin Colon Rectal Surg       Date:  2008-11

7.  Appendiceal intussusception due to an appendiceal malignant polyp--an association in a patient with Peutz-Jeghers syndrome: report of a case.

Authors:  M Miyahara; T Saito; K Etoh; K Shimoda; S Kitano; M Kobayashi; S Yokoyama
Journal:  Surg Today       Date:  1995       Impact factor: 2.549

Review 8.  LKB1 as the ghostwriter of crypt history.

Authors:  Marnix Jansen; Danielle Langeveld; Wendy W J De Leng; Anya N A Milne; Francis M Giardiello; G Johan A Offerhaus
Journal:  Fam Cancer       Date:  2011-09       Impact factor: 2.375

  8 in total

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