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Literature DB >> 662793

Auto-immune neutropenia in an infant.

D S Thompson, P Stableforth, B Darlow, D M Brazier.

Abstract

A case of neutropenia in an infant is described, associated with repeated minor infections which responded to treatment with antibiotics. A granulocyte agglutinin was detected in the serum. Following treatment with prednisolone the neutropenia remitted, the antibody disappeared and the infections ceased. Treatment was discontinued after three months and the child remained well five months later. Reports of similar cases are reviewed and the significance of the antibody discussed.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1978 PMID： 662793 PMCID： PMC2425253 DOI： 10.1136/pgmj.54.630.278

Source DB: PubMed Journal: Postgrad Med J ISSN： 0032-5473 Impact factor: 2.401

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References

11 in total

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Journal: J Pediatr Date: 1975-08 Impact factor: 4.406

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Authors: P Lalezari; A F Jiang; L Yegen; M Santorineou
Journal: N Engl J Med Date: 1975-10-09 Impact factor: 91.245

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Journal: Vox Sang Date: 1958-05 Impact factor: 2.144

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Authors: R Dixon; W Rosse; L Ebbert
Journal: N Engl J Med Date: 1975-01-30 Impact factor: 91.245

Auto-immune neutropenia in an infant.

1. Autoimmune neutropenia in an infant.

2. Chronic autoimmune neutropenia due to anti-NA2 antibody.

3. The incidence and significance of complete and incomplete white cell antibodies with special reference to the use of the Coombs consumption test.

4. Quantitative determination of antibody in idiopathic thrombocytopenic purpura. Correlation of serum and platelet-bound antibody with clinical response.

5. Cytotoxic antibodies against leucocytes.

6. Neutrophil-specific antigens: immunology and clinical significance.

7. Letter: Granulocytopenia and no infections.

8. Leucocyte function in a case of chronic benign neutropenia of infancy associated with circulating leucoagglutinins.

9. Autoimmune neutropenia.

10. Effects of anti-human neutrophil antibodies in vitro. Quantitative studies.