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Literature DB >> 6627519

Studies on the antitumor cyclic hexapeptides obtained from Rubiae radix.

H Itokawa, K Takeya, K Mihara, N Mori, T Hamanaka, T Sonobe, Y Iitaka.

Abstract

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Year: 1983 PMID： 6627519 DOI： 10.1248/cpb.31.1424

Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645

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9 in total

1. Cyclopeptide RA-V inhibits angiogenesis by down-regulating ERK1/2 phosphorylation in HUVEC and HMEC-1 endothelial cells.

Authors: Grace G L Yue; Jun-Ting Fan; Julia K M Lee; Guang-Zhi Zeng; Tina W F Ho; Kwok-Pui Fung; Ping-Chung Leung; Ning-Hua Tan; Clara B S Lau
Journal: Br J Pharmacol Date: 2011-12 Impact factor: 8.739

2. Production of monoclonal antibodies against antitumor cyclohexapeptide RA-VII from Rubia cordifolia and their characterization.

Authors: Tomoyo Hasuda; Yukio Hitotsuyanagi; Koichi Takeya
Journal: J Nat Med Date: 2011-02-08 Impact factor: 2.343

3. Activity of RA-700, a cyclic hexapeptide from Rubiae Radix, in the human tumor clonogenic assay.

Authors: K Inoue; T Mukaiyama; T Kobayashi; M Ogawa
Journal: Invest New Drugs Date: 1986 Impact factor: 3.850

4. Rubipodanin A, the First Natural N-Desmonomethyl Rubiaceae-Type Cyclopeptide from Rubia podantha, Indicating an Important Role of the N9-Methyl Group in the Conformation and Bioactivity.

Authors: Zhe Wang; Si-Meng Zhao; Li-Mei Zhao; Xiao-Qiang Chen; Guang-Zhi Zeng; Ning-Hua Tan
Journal: PLoS One Date: 2015-12-22 Impact factor: 3.240

Studies on the antitumor cyclic hexapeptides obtained from Rubiae radix.

1. Cyclopeptide RA-V inhibits angiogenesis by down-regulating ERK1/2 phosphorylation in HUVEC and HMEC-1 endothelial cells.

2. Production of monoclonal antibodies against antitumor cyclohexapeptide RA-VII from Rubia cordifolia and their characterization.

3. Activity of RA-700, a cyclic hexapeptide from Rubiae Radix, in the human tumor clonogenic assay.

4. Rubipodanin A, the First Natural N-Desmonomethyl Rubiaceae-Type Cyclopeptide from Rubia podantha, Indicating an Important Role of the N9-Methyl Group in the Conformation and Bioactivity.

5. Crosstalk of Cancer Signaling Pathways by Cyclic Hexapeptides and Anthraquinones from Rubia cordifolia.

6. Anthraquinones from the Aerial Parts of Rubia cordifolia with Their NO Inhibitory and Antibacterial Activities.

Review 7. Dihydronaphthofurans: synthetic strategies and applications.

8. Structural and bioactive studies of terpenes and cyclopeptides from the Genus Rubia.

Review 9. Design and synthesis of analogues of RA-VII-an antitumor bicyclic hexapeptide from Rubiae radix.