Literature DB >> 6626894

Permeability and ultrastructure of human bladder epithelium.

J Eldrup, J Thorup, S L Nielsen, T Hald, B Hainau.   

Abstract

Leakage of tight junctions as observed with electron microscopy and demonstration of solute transport across bladder epithelium was investigated in 13 patients with different bladder diseases: urinary retention and infection, bladder tumours and interstitial cystitis. The latter group showed consistent leakage of solutes through the urothelium. Electron microscopy revealed leaky tight junctions. This finding might be helpful in establishing the histological criteria and explain the pathogenesis of interstitial cystitis.

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Year:  1983        PMID： 6626894     DOI： 10.1111/j.1464-410x.1983.tb03354.x

Source DB:  PubMed          Journal:  Br J Urol        ISSN： 0007-1331


  25 in total

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2.  In the absence of overt urothelial damage, chondroitinase ABC digestion of the GAG layer increases bladder permeability in ovariectomized female rats.

Authors:  Robert E Hurst; Samuel Van Gordon; Karl Tyler; Bradley Kropp; Rheal Towner; HsuehKung Lin; John O Marentette; Jane McHowat; Ehsan Mohammedi; Beverley Greenwood-Van Meerveld
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Review 3.  Pentosanpolysulphate for interstitial cystitis.

Authors:  J W Barrington; T P Stephenson
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  1997

4.  Abnormalities in Expression of Structural, Barrier and Differentiation Related Proteins, and Chondroitin Sulfate in Feline and Human Interstitial Cystitis.

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5.  State of the art in intravesical therapy for lower urinary tract symptoms.

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6.  Normalization of proliferation and tight junction formation in bladder epithelial cells from patients with interstitial cystitis/painful bladder syndrome by d-proline and d-pipecolic acid derivatives of antiproliferative factor.

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7.  Structure-Activity Studies on Antiproliferative Factor (APF) Glycooctapeptide Derivatives.

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8.  Low-molecular-weight inhibitor of in vitro fibroblast colony formation from human urine.

Authors:  B W Steinert; J E Robinson; B A Mitchell; A C Diokno
Journal:  World J Urol       Date:  1996       Impact factor: 4.226

9.  The effects of pH changes on human and ferret detrusor muscle function.

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Journal:  J Physiol       Date:  1991-01       Impact factor: 5.182

10.  Importance of TNF-related apoptosis-inducing ligand in pathogenesis of interstitial cystitis.

Authors:  Omer Kutlu; Erdem Akkaya; Ismail Turker Koksal; Ibrahim Cumhur Bassorgun; Mehmet Akif Ciftcioglu; Salih Sanlioglu; Erdal Kukul
Journal:  Int Urol Nephrol       Date:  2009-08-25       Impact factor: 2.370
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