Literature DB >> 6626438

The effect of cimetidine on tolbutamide kinetics.

N G Dey, C M Castleden, J Ward, J Cornhill, A McBurney.   

Abstract

Although possible on theoretical grounds, no interaction between cimetidine and tolbutamide could be demonstrated in ten healthy volunteers. The plasma tolbutamide concentrations over 12 h following 0.5 g orally were essentially the same before and after 1 and 7 days cimetidine (400 mg twice daily).

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Year:  1983        PMID： 6626438      PMCID： PMC1428018          DOI： 10.1111/j.1365-2125.1983.tb02192.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  5 in total

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Authors:  A M Heagerty; M A Donovan; C M Castleden; J F Pohl; L Patel; A Hedges
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3.  Determination of serum tolbutamide and chlorpropamide by high-performance liquid chromatography.

Authors:  R E Hill; J Crechiolo
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4.  The effect of cimetidine on in vitro and in vivo microsomal drug metabolism in the rat.

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Review 5.  Clinical pharmacology of sulphonylurea hypoglycaemic agents: part 1.

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Journal:  Drugs       Date:  1981-09       Impact factor: 9.546
  5 in total
  13 in total

Review 1.  Clinical relevance of cimetidine drug interactions.

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Journal:  Clin Pharmacokinet       Date:  1990-08       Impact factor: 6.447

3.  Lack of efficacy of cimetidine and ranitidine as inhibitors of tolbutamide metabolism.

Authors:  G I Adebayo; H A Coker
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4.  Inhibition and induction of metronidazole and antipyrine metabolism.

Authors:  S Loft; J Sonne; H E Poulsen; K T Petersen; B G Jørgensen; M Døssing
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5.  The paradoxical effect of cimetidine and ranitidine on glibenclamide pharmacokinetics and pharmacodynamics.

Authors:  R T Kubacka; E J Antal; R P Juhl
Journal:  Br J Clin Pharmacol       Date:  1987-06       Impact factor: 4.335

Review 6.  Oral antidiabetic drug use in the elderly.

Authors:  R Bressler; D G Johnson
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7.  Specificity of the inhibitory effect of dextropropoxyphene on oxidative drug metabolism in man: effects on theophylline and tolbutamide disposition.

Authors:  R A Robson; J O Miners; A G Whitehead; D J Birkett
Journal:  Br J Clin Pharmacol       Date:  1987-06       Impact factor: 4.335

Review 8.  Pharmacokinetic interactions of cimetidine 1987.

Authors:  A Somogyi; M Muirhead
Journal:  Clin Pharmacokinet       Date:  1987-05       Impact factor: 6.447

9.  Effects of cimetidine on carbamazepine auto- and hetero-induction in man.

Authors:  G J Macphee; G G Thompson; G Scobie; E Agnew; B K Park; T Murray; K E McColl; M J Brodie
Journal:  Br J Clin Pharmacol       Date:  1984-09       Impact factor: 4.335

10.  Lack of inhibition of tolbutamide hydroxylation by cimetidine in man.

Authors:  C Stockley; J Keal; P Rolan; F Bochner; A Somogyi
Journal:  Eur J Clin Pharmacol       Date:  1986       Impact factor: 2.953
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