| Literature DB >> 6626276 |
E L Winston, K M Pariser, K B Miller, D N Salem, M A Creager.
Abstract
Eight patients with Raynaud's phenomenon were entered into a double-blind crossover study of nifedipine versus placebo, with 7 patients undergoing finger plethysmography before and after sublingual nifedipine administration. While receiving nifedipine, all patients reported decreased frequency and severity of attacks, and 4 of 5 had digital ulcer healing. Total finger blood flow increased 5 of 6 patients after treatment with sublingual nifedipine. This preliminary study indicates that nifedipine may be a useful agent for treatment of digital vasospasm.Entities:
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Year: 1983 PMID： 6626276 DOI： 10.1002/art.1780261001
Source DB: PubMed Journal: Arthritis Rheum ISSN： 0004-3591