Literature DB >> 6623538

Renal excretion of fluoride during water diuresis and induced urinary pH-changes in man.

P O Järnberg, J Ekstrand, M Ehrnebo.   

Abstract

Fluoride renal clearance (CF) was studied in young healthy subjects with standard clearance technique following administration of 3 mg F as a 30-min constant infusion. High urinary flow rates were induced and experiments were performed under both urinary alkaline and acidic conditions. The data showed that a high urinary flow resulted in maximum fluoride clearance. High water diuresis may therefore be an important part in the treatment of acute fluoride intoxication.

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Year:  1983        PMID: 6623538     DOI: 10.1016/0378-4274(83)90084-x

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN: 0378-4274            Impact factor:   4.372


  3 in total

Review 1.  Acid and alkaline diuresis. When are they of value in the treatment of poisoning?

Authors:  L K Garrettson; R J Geller
Journal:  Drug Saf       Date:  1990 May-Jun       Impact factor: 5.606

2.  Occupational fluoride exposure and plasma fluoride levels in man.

Authors:  M Ehrnebo; J Ekstrand
Journal:  Int Arch Occup Environ Health       Date:  1986       Impact factor: 3.015

3.  Compartmental-modelling-based measurement of murine glomerular filtration rate using 18F-fluoride PET/CT.

Authors:  Hyo Sang Lee; Yeon-Koo Kang; Hyunjong Lee; Jeong Hee Han; Byung Seok Moon; Seok-Soo Byun; Dong-Wan Chae; Keon Wook Kang; Won Woo Lee
Journal:  Sci Rep       Date:  2019-08-02       Impact factor: 4.379

  3 in total

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