| Literature DB >> 6623079 |
J R Farley, J E Wergedal, D J Baylink.
Abstract
Fluoride is one of the most potent but least well understood stimulators of bone formation in vivo. Bone formation was shown to arise from direct effects on bone cells. Treatment with sodium fluoride increased proliferation and alkaline phosphatase activity of bone cells in vitro and increased bone formation in embryonic calvaria at concentrations that stimulate bone formation in vivo.Entities:
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Year: 1983 PMID: 6623079 DOI: 10.1126/science.6623079
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728