Literature DB >> 6622977

Amrinone-mediated thrombocytopenia.

E L Kinney, J O Ballard, B Carlin, R Zelis.   

Abstract

Amrinone, a new cardioactive drug, was administered for, on average, 27.9 d to 12 patients in severe congestive heart failure. Thrombocytopenia occurred in 4 patients, while a progressive decline in platelet numbers developed in 3 additional patients. The mechanism for these adverse effects of amrinone is unclear, but merits further study because of its frequency.

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Year:  1983        PMID: 6622977     DOI: 10.1111/j.1600-0609.1983.tb00665.x

Source DB:  PubMed          Journal:  Scand J Haematol        ISSN: 0036-553X


  2 in total

1.  The relationship between the pharmacokinetics of amrinone in the marmoset and platelet effects.

Authors:  C T Eason; J I Usansky; G P Henry; P Powles; F W Bonner
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1988 Apr-Jun       Impact factor: 2.441

Review 2.  Adverse effects associated with the newer inotropic agents.

Authors:  M W Webster; D N Sharpe
Journal:  Med Toxicol       Date:  1986 Sep-Oct
  2 in total

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