Literature DB >> 6622340

Extreme metabolic alkalosis with fludrocortisone therapy.

A Burns, T M Brown, P Semple.   

Abstract

We present an unusual case of extreme metabolic alkalosis resulting from severe hypokalaemia caused by unmonitored fludrocortisone therapy. Biochemical aspects of the disorder are discussed, as is the successful treatment with diuretics and potassium replacement. Some dangers of this therapy and necessary precautions are emphasized.

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Year:  1983        PMID： 6622340      PMCID： PMC2417584          DOI： 10.1136/pgmj.59.694.506

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  10 in total

1.  Hypercapnia in metabolic alkalosis.

Authors:  M Fulop
Journal:  N Y State J Med       Date:  1976-01

2.  Mineralocorticoid-induced blood pressure, electrolyte, and hormone changes, and reversal with spironolactone, in healthy men.

Authors:  M G Nicholls; L E Ramsay; K Boddy; R Fraser; J J Morton; J I Robertson
Journal:  Metabolism       Date:  1979-05       Impact factor: 8.694

3.  The relationship between arterial pCO2 and hydrogen ion concentration in chronic metabolic acidosis and alkalosis.

Authors:  J M Bone; J Cowie; A T Lambie; J S Robson
Journal:  Clin Sci Mol Med       Date:  1974-01

4.  Hypoxia and hypercapnia caused by respiratory compensation for metabolic alkalosis.

Authors:  L Shear; I S Brandman
Journal:  Am Rev Respir Dis       Date:  1973-05

5.  On the pathogenesis of metabolic alkalosis in hyperaldosteronism.

Authors:  J P Kassirer; A M London; D M Goldman; W B Schwartz
Journal:  Am J Med       Date:  1970-09       Impact factor: 4.965

6.  Respiratory adjustment to chronic metabolic alkalosis in man.

Authors:  R M Goldring; P J Cannon; H O Heinemann; A P Fishman
Journal:  J Clin Invest       Date:  1968-01       Impact factor: 14.808

7.  Therapeutic experience with fludrocortisone in diabetic postural hypotension.

Authors:  I W Campbell; D J Ewing; B F Clarke
Journal:  Br Med J       Date:  1976-04-10

8.  Mineralocorticoid-induced hypertension in patients with orthostatic hypotension.

Authors:  A V Chobanian; L Volicer; C P Tifft; H Gavras; C S Liang; D Faxon
Journal:  N Engl J Med       Date:  1979-07-12       Impact factor: 91.245

9.  The treatment of idiopathic orthostatic hypotension: a combined fludrocortisone and flurbiprofen regime.

Authors:  S J Watt; J E Tooke; C M Perkins; M R Lee
Journal:  Q J Med       Date:  1981

10.  Mixed acid base disturbances: a clinical approach.

Authors:  M Bia; S O Thier
Journal:  Med Clin North Am       Date:  1981-03       Impact factor: 5.456
  10 in total

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