Literature DB >> 6621098

Recovering the parameters of finite mixtures of normal distributions from a noisy record: an empirical comparison of different estimating procedures.

L Ling, D J Tolhurst.   

Abstract

Three procedures were compared for their ability to estimate the known parameters of mixtures of normal distributions: maximum likelihood estimators (MLE), X2 minimization method and the least-square error procedure. For this purpose a Monte-Carlo study was undertaken to evaluate empirically the performance of the estimators. We chose to investigate their behaviour using closely-positioned mixtures of two or 3 univariate Gaussians. The Monte-Carlo simulations clearly demonstrate the superiority of the MLE and X2 minimum methods. Other reasons why the MLE is to be preferred are discussed. The effect of sample size was also examined. All 3 estimators have also been applied to data derived from different physiological experiments, and the use of the estimators is considered in practical terms. The formulae for all 3 procedures are given in the Appendix.

Mesh:

Year:  1983        PMID: 6621098     DOI: 10.1016/0165-0270(83)90090-0

Source DB:  PubMed          Journal:  J Neurosci Methods        ISSN: 0165-0270            Impact factor:   2.390


  9 in total

1.  Analysis and implications of equivalent uniform approximations of nonuniform unitary synaptic systems.

Authors:  V V Uteshev; J B Patlak; P S Pennefather
Journal:  Biophys J       Date:  2000-12       Impact factor: 4.033

2.  Presynaptic inhibition of synaptic potentials evoked in cat spinal motoneurones by impulses in single group Ia axons.

Authors:  J D Clements; I D Forsythe; S J Redman
Journal:  J Physiol       Date:  1987-02       Impact factor: 5.182

3.  The effects of synaptic noise on measurements of evoked excitatory postsynaptic response amplitudes.

Authors:  L M Wahl; J J Jack; A U Larkman; K J Stratford
Journal:  Biophys J       Date:  1997-07       Impact factor: 4.033

4.  Monosynaptic EPSPs in cat lumbosacral motoneurones from group Ia afferents and fibres descending in the spinal cord.

Authors:  P J Harrison; J J Jack; D M Kullmann
Journal:  J Physiol       Date:  1989-05       Impact factor: 5.182

5.  A cytophotometric analysis of the structure of hypothalamic cell populations in the frog, Rana temporaria (L.), with special reference to seasonal changes in chromatin status.

Authors:  V K Chetverukhin; G V Selivanova; L S Onischenko; T D Vlasova; A L Polenov
Journal:  Histochemistry       Date:  1988

6.  Practical guidance for testing the accuracy of deconvolution results from quantal analysis.

Authors:  C Lüscher; H P Clamann; H R Lüscher
Journal:  Pflugers Arch       Date:  1994-10       Impact factor: 3.657

7.  Presynaptic glutamate receptors depress excitatory monosynaptic transmission between mouse hippocampal neurones.

Authors:  I D Forsythe; J D Clements
Journal:  J Physiol       Date:  1990-10       Impact factor: 5.182

8.  Evaluation of cerebral acetate transport and metabolic rates in the rat brain in vivo using 1H-[13C]-NMR.

Authors:  Anant B Patel; Robin A de Graaf; Douglas L Rothman; Kevin L Behar; Graeme F Mason
Journal:  J Cereb Blood Flow Metab       Date:  2010-02-03       Impact factor: 6.200

9.  Reduction by general anaesthetics of group Ia excitatory postsynaptic potentials and currents in the cat spinal cord.

Authors:  D M Kullmann; R L Martin; S J Redman
Journal:  J Physiol       Date:  1989-05       Impact factor: 5.182

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.