| Literature DB >> 6619884 |
S S Handa, A D Kinghorn, G A Cordell, N R Farnsworth.
Abstract
Three simaroubolides, glaucarubolone (1), holacanthone (2), and isobrucein A (3) were found to be responsible for the cytotoxic and antileukemic activities observed for extracts of the wood stem, stem bark, and twigs of Soulamea soulameoides. Other cytotoxic constituents isolated include a coumarinolignan cleomiscosin A (4) and the hydroxy canthin-6-one derivative 5. Picrasin B (6) was also obtained, but was not active.Entities:
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Year: 1983 PMID： 6619884 DOI： 10.1021/np50027a011
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050