| Literature DB >> 6619881 |
M J Leach, A A Miller, R A O'Donnell, R A Webster.
Abstract
The effect of kindling rats (with an electrical stimulus applied daily to the frontal cortex) on the concentrations of taurine, aspartate, glutamate, glutamine, and gamma-aminobutyric acid has been investigated. When compared with control groups, cortical glutamine concentrations were significantly decreased in kindled rats by approximately 20%. This decrease in glutamine directly correlated with the after-discharge duration (r = 0.84, p = 0.005). The significance of this in relation to glutamate metabolism and kindling is discussed here.Entities:
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Year: 1983 PMID： 6619881 DOI： 10.1111/j.1471-4159.1983.tb00851.x
Source DB: PubMed Journal: J Neurochem ISSN： 0022-3042 Impact factor: 5.372