Literature DB >> 6618686

Adjuvancy of Cremophor Elo in rodents.

J Descotes, P Tachon, A Laschi-Locquerie, J C Evreux.   

Abstract

Cremophor Elo proved as potent as Freund's complete adjuvant for eliciting skin reactivity to bovine serum albumin in guinea pigs. It enhanced delayed hypersensitivity to sheep erythrocytes in mice while hemagglutinin antibody titers were not affected. This adjuvant activity is likely to play a critical role in hypersensitivity reactions to Cremophor-containing drugs, e.g. alphadione.

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Year:  1983        PMID: 6618686     DOI: 10.1159/000234883

Source DB:  PubMed          Journal:  Int Arch Allergy Appl Immunol        ISSN: 0020-5915


  1 in total

1.  Cremophor EL as an adjuvant affecting immunoglobulin class switch in the immune response to the thymus-independent antigen alpha(1- greater than 3) dextran B 1355 S.

Authors:  F Austrup; T Kucharzik; E Kölsch
Journal:  Immunology       Date:  1991-08       Impact factor: 7.397

  1 in total

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