Literature DB >> 6618492

Prevalence of primary adult lactose malabsorption in Hungary.

A Czeizel, G Flatz, S D Flatz.   

Abstract

Lactose absorption capacity was estimated in 820 apparently healthy, well nourished, Hungarian adults and adolescents (560 females, 260 males, aged 16-54 years) using a field version of the lactose tolerance test with breath hydrogen determination. The test identified 497 lactose absorbers with low, and 323 lactose malabsorbers with high hydrogen excretion 120-150 min after an oral load of 50 g lactose. The prevalence of lactose malabsorption in the general Hungarian sample (n = 535) was 37%. In subgroups from the western and eastern Hungarian plains, frequency of lactose malabsorption reached almost 30%. It tended to be higher in Upper Hungary (ca. 40%) and in subjects stemming from former Hungarian areas in the Carpathian bend. Lactose malabsorption in a Hungarian ethnic subgroup, the Matyo (n = 172), did not differ significantly from that in the general population. Among Romai ("Gypsies", n = 113), the prevalence of lactose malabsorption was significantly higher (56%). Awareness of milk intolerance was significantly more frequent, and severe symptoms of lactose intolerance during the test occurred almost exclusively in lactose malabsorbers.

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Year:  1983        PMID: 6618492     DOI: 10.1007/bf00292375

Source DB:  PubMed          Journal:  Hum Genet        ISSN: 0340-6717            Impact factor:   4.132


  9 in total

1.  The human lactase polymorphism: physiology and genetics of lactose absorption and malabsorption.

Authors:  G Flatz; H W Rotthauwe
Journal:  Prog Med Genet       Date:  1977

2.  Lactose nutrition and natural selection.

Authors:  G Flatz; H W Rotthauwe
Journal:  Lancet       Date:  1973-07-14       Impact factor: 79.321

3.  [Disaccharidase activity of the small intestine in the adult].

Authors:  J Madzarovová-Nohejlová
Journal:  Dtsch Z Verdau Stoffwechselkr       Date:  1974

4.  The inheritance of selective adult-type lactose malabsorption.

Authors:  T Sahi
Journal:  Scand J Gastroenterol Suppl       Date:  1974

5.  Primary adult lactose intolerance and the milking habit: a problem in biologic and cultural interrelations. II. A culture historical hypothesis.

Authors:  F J Simoons
Journal:  Am J Dig Dis       Date:  1970-08

6.  Distribution of human adult lactase phenotypes in the population of Austria.

Authors:  W Rosenkranz; B Hadorn; W Müller; P Heinz-Erian; C Hensen; G Flatz
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

Review 7.  Lactose malabsorption: its biology and history.

Authors:  J D Johnson; N Kretchmer; F J Simoons
Journal:  Adv Pediatr       Date:  1974

8.  Distribution of physiological adult lactase phenotypes, lactose absorber and malabsorber, in Germany.

Authors:  G Flatz; J N Howell; J Doench; S D Flatz
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

9.  Distribution of the lactase phenotypes in the population of the Democratic Republic of the Sudan.

Authors:  R A Bayoumi; N Saha; A S Salih; A E Bakkar; G Flatz
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

  9 in total
  3 in total

1.  A study of lactose absorption capacity in twins.

Authors:  J Métneki; A Czeizel; S D Flatz; G Flatz
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

2.  A worldwide correlation of lactase persistence phenotype and genotypes.

Authors:  Yuval Itan; Bryony L Jones; Catherine J E Ingram; Dallas M Swallow; Mark G Thomas
Journal:  BMC Evol Biol       Date:  2010-02-09       Impact factor: 3.260

3.  Latitude, sunshine, and human lactase phenotype distributions may contribute to geographic patterns of modern disease: the inflammatory bowel disease model.

Authors:  Andrew Szilagyi; Henry Leighton; Barry Burstein; Xiaoqing Xue
Journal:  Clin Epidemiol       Date:  2014-05-27       Impact factor: 4.790

  3 in total

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