Literature DB >> 6618270

Histochemical changes in mucus in duodenal ulceration.

S M Morrissey, P M Ward, A P Jayaraj, F I Tovey, C G Clark.   

Abstract

In duodenal ulceration the Alcian blue staining acid mucosubstances in goblet cells are reduced and the goblet cells themselves disappear. At the same time periodic acid-Schiff (PAS) staining neutral mucosubstances appear in the cells of the surface epithelium. These changes have been measured quantitatively with the help of a Vickers M86/0010 Scanning and Integrated Microdensitometer. During healing the changes are reversed. It is suggested that these changes suggest a metaplasia towards a gastric type mucosa as a protective response to the presence of ulceration.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6618270      PMCID： PMC1420154          DOI： 10.1136/gut.24.10.909

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  12 in total

1.  SULPHATED MUCOPOLYSACCHARIDES OF THE GASTRIC SECRETION.

Authors:  J SCHRAGER
Journal:  Nature       Date:  1964-02-15       Impact factor: 49.962

2.  A HISTOCHEMICAL COMPARISON OF HUMAN EPITHELIAL MUCINS IN NORMAL AND IN HYPERSECRETORY STATES INCLUDING PANCREATIC CYSTIC FIBROSIS.

Authors:  R LEV; S S SPICER
Journal:  Am J Pathol       Date:  1965-01       Impact factor: 4.307

3.  The carbohydrate and ester sulfate content of mucosal biopsies in health and in patients with duodenal ulcer.

Authors:  F Andre; D Bouhours; C Andre; F Descos; R Lambert
Journal:  Clin Chim Acta       Date:  1974-11-08       Impact factor: 3.786

4.  Quantitative distribution of various types of acid glycoprotein in mucous cells of human bronchi.

Authors:  D Lamb; L Reid
Journal:  Histochem J       Date:  1972-03

5.  Histochemistry of the colonic epithelial mucins in normal subjects and in patients with ulcerative colitis. A qualitative and histophotometric investigation.

Authors:  V Greco; G Lauro; A Fabbrini; A Torsoli
Journal:  Gut       Date:  1967-10       Impact factor: 23.059

6.  Acid mucins in human intestinal goblet cells.

Authors:  S M Morrissey; M C Tymvios
Journal:  J Pathol       Date:  1978-12       Impact factor: 7.996

7.  GASTRIC EPITHELIUM IN THE DUODENUM.

Authors:  A H JAMES
Journal:  Gut       Date:  1964-08       Impact factor: 23.059

8.  Mucous change in the human duodenum: a light and electron microscopic study and correlation with disease and gastric acid secretion.

Authors:  W J Patrick; D Denham; A P Forrest
Journal:  Gut       Date:  1974-10       Impact factor: 23.059

9.  Histochemical changes in gastric mucosubstances in patients with acute and chronic ulcer disease.

Authors:  R S Cathcart; C T Fitts; J C McAlhany; S S Spicer
Journal:  Ann Surg       Date:  1974-07       Impact factor: 12.969

10.  Changes in the morphology of villar epithelial cells adjacent to duodenal ulcers during the process of healing.

Authors:  M A Gregory; M G Moshal; J M Spitaels
Journal:  Scand J Gastroenterol       Date:  1982-04       Impact factor: 2.423
View more
  9 in total

1.  Duodenal ulceration and postoperative recurrence.

Authors:  F I Tovey; E M Husband; Y C Yiu; L Baker; G McPhail; A P Jayaraj
Journal:  Gut       Date:  1989-06       Impact factor: 23.059

2.  Deformity of duodenal bulb, gastric metaplasia of duodenal regenerating mucosa and recurrence of duodenal ulcer: a correlated study.

Authors:  Chun-Chao Chang; Shiann Pan; Gi-Shih Lien; Cheng-Hsiung Liao; Sheng-Hsuan Chen; Yeong-Shan Cheng
Journal:  World J Gastroenterol       Date:  2005-03-28       Impact factor: 5.742

3.  Comparison of relapse rates and of mucosal abnormalities after healing of duodenal ulceration and after one year's maintenance with cimetidine or sucralfate: a light and electron microscopy study.

Authors:  F I Tovey; E M Husband; Y C Yiu; L Baker; G McPhail; M R Lewin; A P Jayaraj; C G Clark
Journal:  Gut       Date:  1989-05       Impact factor: 23.059

4.  Pyloric metaplasia, pseudopyloric metaplasia, ulcer-associated cell lineage and spasmolytic polypeptide-expressing metaplasia: reparative lineages in the gastrointestinal mucosa.

Authors:  James R Goldenring
Journal:  J Pathol       Date:  2018-04-14       Impact factor: 7.996

5.  The pathophysiology of peptic ulcer disease.

Authors:  F P Brooks
Journal:  Dig Dis Sci       Date:  1985-11       Impact factor: 3.199

6.  Enhancement by tetragastrin of experimental induction of gastric epithelium in the duodenum.

Authors:  M Tatsuta; H Iishi; H Yamamura; R Yamamoto; H Taniguchi
Journal:  Gut       Date:  1989-03       Impact factor: 23.059

7.  Effects of Yersinia enterocolitica infection on rabbit intestinal and colonic goblet cells and mucin: morphometrics, histochemistry, and biochemistry.

Authors:  M Mantle; E Atkins; J Kelly; E Thakore; A Buret; D G Gall
Journal:  Gut       Date:  1991-10       Impact factor: 23.059

8.  Mechanisms of airway responses to esophageal acidification in cats.

Authors:  Ivan M Lang; Steven T Haworth; Bidyut K Medda; Hubert Forster; Reza Shaker
Journal:  J Appl Physiol (1985)       Date:  2016-02-04

Review 9.  Follow the Metaplasia: Characteristics and Oncogenic Implications of Metaplasia's Pattern of Spread Throughout the Stomach.

Authors:  José B Sáenz
Journal:  Front Cell Dev Biol       Date:  2021-11-12
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.