Literature DB >> 6617821

A radioisotopic method for the determination of S-adenosyl-L-homocysteine in tissues in the 10(-7) M range.

P Fonlupt, B Chabannes, O Macovski, H Pacheco.   

Abstract

S-Adenosyl-L-homocysteine is able to bind to brain membranes. We used this characteristic to measure the level of S-adenosyl-L-homocysteine in rat brain tissue. The method is rapid, at the same time very sensitive (down to 10(-7) M) and specific.

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Year:  1983        PMID： 6617821     DOI： 10.1007/bf01943170

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  The enzymatic synthesis of S-adenosyl-L-homocysteine from adenosine and homocysteine.

Authors:  G DE LA HABA; G L CANTONI
Journal:  J Biol Chem       Date:  1959-03       Impact factor: 5.157

2.  The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation.

Authors:  E G GRAY; V P WHITTAKER
Journal:  J Anat       Date:  1962-01       Impact factor: 2.610

3.  A sensitive enzymatic procedure for the quantitative determination of S-adenosylhomocysteine in tissues.

Authors:  P H Yu
Journal:  Anal Biochem       Date:  1978-02       Impact factor: 3.365

4.  SAH analogs, modified in the aminoacid region, inhibitors of phosphatidyl-ethanolamine methylase activity and 3H-SAH binding to rat brain membranes.

Authors:  P Fonlupt; C Rey; H Pacheco
Journal:  Life Sci       Date:  1982-08-16       Impact factor: 5.037

5.  A new method for the assay of tissue. S-adenosylhomocysteine and S-adenosylmethione. Effect of pyridoxine deficiency on the metabolism of S-adenosylhomocysteine, S-adenosylmethionine and polyamines in rat liver.

Authors:  T O Eloranta; E O Kajander; A M Raina
Journal:  Biochem J       Date:  1976-11-15       Impact factor: 3.857

6.  Decreased transmethylation of biogenic amines after in vivo elevation of brain S-adenosyl-l-homocysteine.

Authors:  R A Schatz; T E Wilens; O Z Sellinger
Journal:  J Neurochem       Date:  1981-05       Impact factor: 5.372

7.  In vitro and in vivo binding of S-adenosyl-L-homocysteine to membranes from rat cerebral cortex.

Authors:  P Fonlupt; C Rey; H Pacheco
Journal:  J Neurochem       Date:  1981-01       Impact factor: 5.372

8.  The regional concentrations of S-adenosyl-L-methionine, S-adenosyl-L-homocysteine, and adenosine in rat brain.

Authors:  A Gharib; N Sarda; B Chabannes; L Cronenberger; H Pacheco
Journal:  J Neurochem       Date:  1982-03       Impact factor: 5.372

9.  S-Adenosyl-L-homocysteine in brain : Regional concentrations, catabolism, and the effects of methionine sulfoximine.

Authors:  R A Schatz; C R Vunnam; O Z Sellinger
Journal:  Neurochem Res       Date:  1977-02       Impact factor: 3.996
  9 in total

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