Literature DB >> 6616967

Production of a monoclonal antibody to autoantigenic components of human glomerular basement membrane.

A Pressey, C D Pusey, A Dash, D K Peters, C M Lockwood.   

Abstract

We describe a mouse monoclonal antibody which reacts on immunoblotting with those components of collagenase digested human glomerular basement membrane (GBM) that are also recognized by autoantibodies in sera from patients with anti-GBM nephritis. Competition between the monoclonal antibody and anti-GBM autoantibodies was demonstrated in a solid phase radioimmunoassay, suggesting that both are directed against the same autoantigen.

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Year:  1983        PMID: 6616967      PMCID: PMC1536203     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN: 0009-9104            Impact factor:   4.330


  6 in total

1.  Surface-specific iodination of membrane proteins of viruses and eucaryotic cells using 1,3,4,6-tetrachloro-3alpha,6alpha-diphenylglycoluril.

Authors:  M A Markwell; C F Fox
Journal:  Biochemistry       Date:  1978-10-31       Impact factor: 3.162

2.  Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Authors:  H Towbin; T Staehelin; J Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

3.  A method of trace iodination of proteins for immunologic studies.

Authors:  P J McConahey; F J Dixon
Journal:  Int Arch Allergy Appl Immunol       Date:  1966

4.  Human glomerular basement membrane. Preparation and composition.

Authors:  N G Westberg; A F Michael
Journal:  Biochemistry       Date:  1970-09-15       Impact factor: 3.162

5.  Antibodies to major histocompatibility antigens produced by hybrid cell lines.

Authors:  G Galfre; S C Howe; C Milstein; G W Butcher; J C Howard
Journal:  Nature       Date:  1977-04-07       Impact factor: 49.962

6.  Spatial orientation and distribution of antigens within human glomerular basement membrane.

Authors:  A J Fish; K M Carmody; A F Michael
Journal:  J Lab Clin Med       Date:  1979-09
  6 in total
  6 in total

1.  The gene corresponding to the putative Goodpasture antigen is present in Alport's syndrome.

Authors:  J A Savige
Journal:  Clin Exp Immunol       Date:  1991-08       Impact factor: 4.330

2.  Monoclonal antibodies to rat renal tissue: an approach to the immunohistological analysis of the nephron-collecting duct system, and ultra-structural localization of antigens.

Authors:  T Shimokama; T Watanabe
Journal:  Histochem J       Date:  1991-01

3.  Ricinus communis agglutinin I blocks the binding of human anti-renal basement membrane antibodies to the kidney.

Authors:  K Yoshioka; M Okada; T Takemura; S Maki
Journal:  Am J Pathol       Date:  1987-03       Impact factor: 4.307

4.  Characterization of the human Goodpasture antigen.

Authors:  J Wieslander; M Kataja; B G Hudson
Journal:  Clin Exp Immunol       Date:  1987-08       Impact factor: 4.330

5.  The development of anti-glomerular basement membrane nephritis in two children with Alport's syndrome after renal transplantation: characterization of the antibody target.

Authors:  L P vd Heuvel; C H Schröder; C O Savage; D Menzel; K J Assmann; L A Monnens; J H Veerkamp
Journal:  Pediatr Nephrol       Date:  1989-10       Impact factor: 3.714

6.  An immunohistochemical and electron microscopic study of extra-renal basement membranes in dogs with Samoyed hereditary glomerulopathy.

Authors:  P S Thorner; B Jansen; R Baumal; R V Harrison; R J Mount; V E Valli; P M Spicer; P M Marrano
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1988
  6 in total

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