Literature DB >> 6616875

Apparent gastrointestinal origin of cis-4-hydroxycyclohexanecarboxylic acid.

J B Kronick, O A Mamer, J Montgomery, C R Scriver.   

Abstract

We identified by gas chromatography-mass spectrometry the unusual substance cis-4-hydroxycyclohexanecarboxylic acid (4-HCH) in the urine of a child. Urinary excretion of 4-HCH and intestinal bacteria were both suppressed by neomycin treatment. We propose that 4-HCH is a by-product of bacterial metabolism.

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Year:  1983        PMID： 6616875     DOI： 10.1016/0009-8981(83)90249-8

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN： 0009-8981            Impact factor:   3.786


  1 in total

1.  Hereditary tyrosinaemia type II in a consanguineous Ashkenazi Jewish family: intrafamilial variation in phenotype; absence of parental phenotype effects on the fetus.

Authors:  D Chitayat; A Balbul; V Hani; O A Mamer; C Clow; C R Scriver
Journal:  J Inherit Metab Dis       Date:  1992       Impact factor: 4.982
  1 in total

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