Literature DB >> 6616073

Enhancement of spontaneous and lymphokine activated human macrophage cytotoxicity by hyperthermia.

R Andreesen, J Osterholz, A Schulz, G W Löhr.   

Abstract

Human macrophages grown on hydrophobic teflon membranes from blood-born monocytes were incubated at hyperthermic temperatures for various time periods and then tested for their ability to inhibit the growth of an allogeneic lymphoma cell line (U 937). Incubation at 40.5 degrees C greatly enhanced macrophage cytotoxicity. This effect of hyperthermia developed slowly with an optimal incubation period of 48 h. In addition, lymphokine activation of macrophages for cytotoxicity appeared to be more effective at elevated temperatures.

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Year:  1983        PMID： 6616073     DOI： 10.1007/bf00320841

Source DB:  PubMed          Journal:  Blut        ISSN： 0006-5242


  18 in total

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Journal:  Cancer Res       Date:  1979-05       Impact factor: 12.701

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Journal:  N Engl J Med       Date:  1972-01-06       Impact factor: 91.245

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Journal:  Blood       Date:  1974-08       Impact factor: 22.113

8.  Cytotoxicity of human macrophages for tumor cells. Enhancement by human lymphocyte mediators.

Authors:  D J Cameron; W H Churchill
Journal:  J Clin Invest       Date:  1979-05       Impact factor: 14.808

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Authors:  J B Smith; R P Knowlton; S S Agarwal
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Journal:  Cancer Res       Date:  1981-05       Impact factor: 12.701
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  4 in total

Review 1.  Hyperthermic modulation of macrophage-tumor cell interactions.

Authors:  S P Tomasovic; J Klostergaard
Journal:  Cancer Metastasis Rev       Date:  1989-12       Impact factor: 9.264

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Authors:  A Müllbacher
Journal:  J Virol       Date:  1984-12       Impact factor: 5.103

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Authors:  H Yoshioka; S Koga; M Maeta; N Shimizu; R Hamazoe; A Murakami
Journal:  Jpn J Surg       Date:  1990-01

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Authors:  C A Dinarello; P Conti; J W Mier
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  4 in total

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