| Literature DB >> 6616025 |
P Farina, E Benfenati, R Reginato, L Torti, M D'Incalci, M D Threadgill, A Gescher.
Abstract
High pressure liquid chromatography was used in combination with mass spectrometry to confirm that the main products of in vitro metabolism of 1-(4-acetylphenyl)-3,3-dimethyltriazene are 1-(4-acetylphenyl-3-methyltriazene and 4-aminoacetophenone. In addition a novel metabolite, 1-[4-(1-hydroxyethyl)-phenyl]-3,3-dimethyltriazene, possessing antitumour activity similar to the parent drug, was identified.Entities:
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Year: 1983 PMID： 6616025 DOI： 10.1002/bms.1200100808
Source DB: PubMed Journal: Biomed Mass Spectrom ISSN： 0306-042X