Literature DB >> 6616024

Determination of histamine by chemical ionization mass spectrometry: application to human urine.

J J Keyzer, H Breukelman, H Elzinga, B J Koopman, B G Wolthers, A P Bruins.   

Abstract

A determination of histamine in urine by selected ion monitoring, using (15N2)histamine as internal standard, is described. Three different ionization methods were used, chemical ionization with ammonia as reactant gas offering the highest sensitivity (detection limit 40 fmol of histamine on column). The 24 h urinary excretions of 10 normal adults ranged from 142-1100 nmol (mean 321 nmol). Patients with an anaphylactoid reaction and patients with mastocytosis showed above normal values.

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Year:  1983        PMID： 6616024     DOI： 10.1002/bms.1200100807

Source DB:  PubMed          Journal:  Biomed Mass Spectrom        ISSN： 0306-042X


  4 in total

Review 1.  Aspects of histamine metabolism.

Authors:  J P Green; G D Prell; J K Khandelwal; P Blandina
Journal:  Agents Actions       Date:  1987-10

2.  Influence of decontamination of the digestive tract on the urinary excretion of histamine and some of its metabolites.

Authors:  J J Keyzer; H K van Saene; G A van den Berg; B G Wolthers
Journal:  Agents Actions       Date:  1984-10

3.  Histamine in tears: developments in collection and HPLC-fluorimetric detection.

Authors:  M R Angi; A Bettero; C A Benassi
Journal:  Agents Actions       Date:  1985-04

4.  Urinary excretion of histamine and some of its metabolites in man: influence of the diet.

Authors:  J J Keyzer; H Breukelman; B G Wolthers; M van den Heuvel; N Kromme; W C Berg
Journal:  Agents Actions       Date:  1984-10
  4 in total

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