Literature DB >> 6615469

Age-related changes in the structure of proteoglycan link proteins present in normal human articular cartilage.

J S Mort, A R Poole, P J Roughley.   

Abstract

Link proteins were identified immunologically in human articular-cartilage protein preparations from various individuals. Irrespective of age, all cartilages contained three link proteins of mol.wts. 48000, 44000 and 41000. However, with increasing age, multiple additional components of mol.wts. 26000-30000 were commonly observed under conditions where disulphide bonds were reduced.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6615469      PMCID： PMC1152237          DOI： 10.1042/bj2140269

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  20 in total

1.  The purification and cyanogen bromide cleavage of the 'link proteins' from cartilage proteoglycan.

Authors:  J Baker; B Caterson
Journal:  Biochem Biophys Res Commun       Date:  1977-07-11       Impact factor: 3.575

2.  Heterogeneity of proteoglycans in developing chick limb cartilage.

Authors:  N S Vasan; J W Lash
Journal:  Biochem J       Date:  1977-04-15       Impact factor: 3.857

3.  Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane.

Authors:  G Fairbanks; T L Steck; D F Wallach
Journal:  Biochemistry       Date:  1971-06-22       Impact factor: 3.162

4.  The specific interaction of hyaluronic acid with cartillage proteoglycans.

Authors:  T E Hardingham; H Muir
Journal:  Biochim Biophys Acta       Date:  1972-09-15

5.  Multiple aggregation factors in cartilage proteoglycan.

Authors:  J D Gregory
Journal:  Biochem J       Date:  1973-06       Impact factor: 3.857

6.  Correlations between stiffness and the chemical constituents of cartilage on the human femoral head.

Authors:  G E Kempson; H Muir; S A Swanson; M A Freeman
Journal:  Biochim Biophys Acta       Date:  1970-07-21

7.  Polypeptides of the tail fibres of bacteriophage T4.

Authors:  J King; U K Laemmli
Journal:  J Mol Biol       Date:  1971-12-28       Impact factor: 5.469

8.  Isolation and characterization of proteoglycans from the swarm rat chondrosarcoma.

Authors:  T R Oegema; V C Hascall; D D Dziewiatkowski
Journal:  J Biol Chem       Date:  1975-08-10       Impact factor: 5.157

9.  Isolation and chemical characterization of two distinct "link proteins" from bovine nasal cartilage proteoglycan complex.

Authors:  F Bonnet; J P Périn; P Jollès
Journal:  Biochim Biophys Acta       Date:  1978-02-15

10.  Immunochemistry of cartilage proteoglycan. Immunodiffusion and gel-electrophoretic studies.

Authors:  H Keiser; H J Shulman; J I Sandson
Journal:  Biochem J       Date:  1972-01       Impact factor: 3.857
View more
  29 in total

1.  Link protein as a monitor in situ of endogenous proteolysis in adult human articular cartilage.

Authors:  Q Nguyen; J Liu; P J Roughley; J S Mort
Journal:  Biochem J       Date:  1991-08-15       Impact factor: 3.857

2.  Cartilage proteoglycan aggregate is degraded more extensively by cathepsin L than by cathepsin B.

Authors:  Q Nguyen; J S Mort; P J Roughley
Journal:  Biochem J       Date:  1990-03-01       Impact factor: 3.857

3.  The absence of type II collagen and changes in proteoglycan structure of hyaline cartilage in a case of Langer-Saldino achondrogenesis.

Authors:  S P Feshchenko; I A Rebrin; V P Sokolnik; B M Sher; B P Sokolov; V N Kalinin; G I Lazjuk
Journal:  Hum Genet       Date:  1989-04       Impact factor: 4.132

4.  Degradation of proteoglycan aggregate by a cartilage metalloproteinase. Evidence for the involvement of stromelysin in the generation of link protein heterogeneity in situ.

Authors:  Q Nguyen; G Murphy; P J Roughley; J S Mort
Journal:  Biochem J       Date:  1989-04-01       Impact factor: 3.857

5.  The identification and characterization of two populations of aggregating proteoglycans of high buoyant density isolated from post-natal human articular cartilages of different ages.

Authors:  C Webber; T T Glant; P J Roughley; A R Poole
Journal:  Biochem J       Date:  1987-12-15       Impact factor: 3.857

Review 6.  Proteoglycans in health and disease: structures and functions.

Authors:  A R Poole
Journal:  Biochem J       Date:  1986-05-15       Impact factor: 3.857

7.  Identification of a hyaluronic acid-binding protein that interferes with the preparation of high-buoyant-density proteoglycan aggregates from adult human articular cartilage.

Authors:  P J Roughley; R J White; A R Poole
Journal:  Biochem J       Date:  1985-10-01       Impact factor: 3.857

8.  Matrix metalloproteinases cleave at two distinct sites on human cartilage link protein.

Authors:  Q Nguyen; G Murphy; C E Hughes; J S Mort; P J Roughley
Journal:  Biochem J       Date:  1993-10-15       Impact factor: 3.857

9.  The properties of proteoglycan prepared from human articular cartilage by using associative caesium chloride gradients of high and low starting densities.

Authors:  M T Bayliss; P J Roughley
Journal:  Biochem J       Date:  1985-11-15       Impact factor: 3.857

10.  Metalloproteinase digestion of cartilage proteoglycan. Pattern of cleavage by stromelysin and susceptibility to collagenase.

Authors:  C Hughes; G Murphy; T E Hardingham
Journal:  Biochem J       Date:  1991-11-01       Impact factor: 3.857
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.